Phytochemistry, Traditional Uses and Pharmacological Profile of Rose Hip: A Review

Abstract

Background: The fruit of genus Rosa, known as "rose hip", is frequently used in different traditional medicines. Rose hips have long been used to treat kidney stones, gastroenteric ailments, hypertension and respiratory problems such as bronchitis, cough and cold. Aim: This review is focused on the ethnopharmacological uses of rose hip as well as phytochemical and pharmacological aspects. Results: Ethno-medical uses of rose hip have been recorded in many countries since a long time. Approximately, 129 chemical compounds have been isolated and identified from rose hip. This fruit contains some major active components such as flavonoids, tannins, anthocyanin, phenolic compounds, fatty oil, organic acids and inorganic compounds. Scientific studies have suggested a wide range of pharmacological activities for rose hip including antioxidant, anti-inflammatory, anti-obesity, anti-cancer, hepatoprotective, nephroprotective, cardioprotective, antiaging, anti H. pylori, neuroprotective and antinociceptive activities. In particular, the rose hip powder and extract have been reported to exert therapeutic effects on arthritis. Conclusion: Some of the ethnomedical indications of rose hip, such as nephroprotective and gastroproetctive actions, have been confirmed by preclinical pharmacological studies. Additional investigations on the pharmacological effects of rose hip as well as evidence from randomized controlled trials are essential to assess the therapeutic value of this natural product.

Rhizosphere microbial communities associated to rose replant disease: links to plant growth and root metabolites

“…Likewise, the data confirm a previous study that reported the presence of catechin, epicatechin, and various other prominent polyphenols (e.g., phlorizin and phloretin) in rose roots and root tips 35 . Gallic acid, commonly acting as an antioxidant, was detected in rose hips 15 . Phlorizin showed a clear trend of higher concentrations in roots grown in G soils (Fig.…”

“…Analyses of secondary metabolites so far carried out in Rosa sp. were related to the pharmaceutical use of roses 15,16 . However, only little information is available about phytoalexins in roses.…”

Management Pearls on the Treatment of Actinic Keratoses and Field Cancerization

“…We suggest keeping these creams in the refrigerator or, alternatively, to immersing them in ice water before the procedure. Products containing triterpenes of gotu kola with rosehip oil are the best options [ 33 , 45 ]. Use non-ablative energy devices, such as intense pulsed light or the non-ablative erbium:glass fiber 1550 nm laser system, as part of the treatment for photodamaged skin in patients for whom the recovery time due to their occupation needs to be very short or minimal and who cannot have a prolonged desquamation or appearance of dark scabs as occurs with ablative laser or CP.…”

“…We suggest keeping these creams in the refrigerator or, alternatively, to immersing them in ice water before the procedure. Products containing triterpenes of gotu kola with rosehip oil are the best options [ 33 , 45 ].…”

Non-food cropRosa canina Lleaf and twig extracts as a source of nutrients and bioactive compounds

“…HPLC analysis has shown R. canina hips extract to be especially rich in the polyphenols hyperoside, astragalin, rutin, (+)-catechin and (-)-epicatechin, gallic acid and poly-hydroxylated organic acids such as quinic acid [28,29]. The phenolic compouds (+)-catechin, (-)-epicatechin, rutin, vanillin, astragalin, phloridzin and gallic acid, identified in hips extract, have been reported as strong scavengers of the ROO - radical [30].…”