Phytochemistry and pharmacology of sea buckthorn (Elaeagnus rhamnoides; syn. Hippophae rhamnoides): progress from 2010 to 2021

Abstract

Sea buckthorn (Elaeagnus rhamnoides; syn. Hippophae rhamnoides) is a thorny shrub or a small tree belonging to the Elaeagnaceae family, native to Eurasia. Sea buckthorn fruit is rich in vitamins and minerals, oils from the seeds and fruit flesh find use in medicine and the cosmetic industry or as nutraceutical supplements. Fruit, leaves and other parts of buckthorn have been used in traditional medicine, especially in China, Tibet, Mongolia, and Central Asia countries, and are a rich source of many bioactive substances. Due to its health-promoting and medicinal properties, the plant has been extensively investigated for several decades, and its phytochemical composition and pharmacological properties are well characterized. The years 2010–2021 brought significant progress in phytochemical research on sea buckthorn. Dozens of new compounds, mainly phenolics, were isolated from this plant. Numerous pharmacological studies were also performed, investigating diverse aspects of the biological activity of different extracts and natural products from sea buckthorn. This review focuses on the progress in research on sea buckthorn specialized metabolites made in this period. Pharmacological studies on sea buckthorn are also discussed. In addition, biosynthetic pathways of the main groups of these compounds have been shortly described. Graphical abstract

The Potential of Medicinal Plants and Natural Products in the Treatment of Burns and Sunburn—A Review

“…It is used mainly due to its anti-diabetic, anti-obesity, and cardiovascular-improving properties. When used topically on the skin, its protective effect against solar radiation is emphasised [ 26 , 27 ].…”

Effect of Polyphenols in Sea Buckthorn Berry on Chemical Mediator Release from Mast Cells

“…SBB is rich in bioactive compounds and has been traditionally used in China and Mongolia to treat asthma and skin conditions ( Singh et al, 2011 ). Flavonols such as kaempferol, quercetin, and isorhamnetin in SBB are associated with its physiological functions ( Żuchowski, 2023 ). We aimed to clarify the antiallergic effects of SBB using cell lines and identify the active compounds that contribute to the inhibitory activity.…”

“…SBB has been shown to exhibit antioxidant, antibacterial, and antiviral effects ( Olas et al, 2016 ; Yue et al, 2017 ; Kurskaya et al, 2022 ) and is expected to have a high therapeutic and medicinal potential ( Suryakumar and Gupta, 2011 ). However, the immunomodulatory effects of SBB have been little studied ( Geetha et al, 2002 ; Żuchowski, 2023 ). In previous studies, many compounds including polyphenols, have been isolated from SBB, with its flavonoid profile primarily comprising isorhamnetin, quercetin, and kaempferol glycosides ( Fang et al, 2013 ; Gu et al, 2022 ).…”

Comparative quantitative analysis of fruit oil from Hippophae rhamnoides (seabuckthorn) by qNMR, FTIR and GC–MS

“…Different parts of SBT, namely leaves, fruits, pulp and seeds have been reported for various classes of bioactive compounds, which are lipophilic to hydrophilic in nature. It is a rich source of flavonoids, carotenoids, pigments, minerals, amino acids, fatty acids and phytosterols ( Yuzhen and Fuheng, 1997 , Teleszko et al, 2015 , Żuchowski, 2023 ). The patents on a number of pharmacological activities, like cardiovascular, antioxidant, anti-inflammatory, antiulcer, anticancer, antihypertensive, radioprotective, anti-ulcer, antibacterial and etc, have recently been reviewed ( Singh et al, 2019 , El-Sohaimy et al, 2022 ), highlighting the important health benefits of this plant.…”