Phytochemistry and Heamatological Potential of Ethanol Seed Leaf and Pulp Extracts of Carica papaya (Linn.)

Abstract

This study was aimed at qualitative evaluation of the ethanol seed, leaf and pulp extracts of C. papaya for bioactive compounds and also to investigate their effect on the haematology in male albino rats. A 3 x 4 factorial experimental layout using randomized complete design was adopted. Results show that the phytochemicals found in seed, leaf and pulp were almost the same but however, in varying proportions. Present result also revealed that there were significant effects (p < 0.05) of the extracts on the heamatology of the treated rats, which was blamed on the varying and different variants ofbioactive compounds found in the extracts they were administered with. Suggestively, C. papaya extracts could be used to enhance the production of selected blood parameters, taking issue of dosage into consideration.

<i>In vitro</i> antiplasmodial and cytotoxic properties of some medicinal plants from western Burkina Faso

“…As shown in previous studies, in traditional medicine practice, medicinal plants can be used but the dosage must be taken into consideration. 46,47 The results of this study can improve the traditional use of plants and protect people from risks following their administration.…”

Phytochemistry and Reproductive Activities of Male Albino Rats Treated with Crude Leaf Extract of Great Bougainvillea (Bougainvillea spectabilis)

“…Although, there is much interest on the use of plant products to control disease conditions such as diabetes, infertility, cancer, inflammation, etc., Ikpeme et al (2014), Ravi et al (2012) and Nagavani et al (2010), it should be noted that it may also generate adverse pharmacological effects on sperm profile of the organism as evidenced in our results. It is reported that some medicinal plants disrupt spermatogenic pathways, which might eventually lead to decreased sperm count, viability, motility (Ikpeme et al, 2007(Ikpeme et al, , 2010(Ikpeme et al, , 2014Ekaluo et al, 2009). This suggests that the administration of extract to the rats may have resulted in the alteration of spermatogenesis resulting in reduction of the sperm count from 9.380×10 Asian J.…”

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