Phytochemistry and antibacterial efficacy of northeastern pakistani artemisia rutifolia stephan ex spreng. extracts against some clinical and phyto-pathogenic bacterial strains

Anti-MRSA and cytotoxic activities of different solvent extracts from Artemisia herba-alba grown in Shubak, Jordan

“…In general, Gram-positive bacterial strains were inhibited by all extracts while Gram-negative bacteria were inhibited only by n -hexane and dichloromethane extracts. This result was consistent with other studies, which showed that n -hexane-based plant extracts had higher antibacterial activity compared to the other solvents extract ( Hussain et al , 2022 ). Also, this result is consistent with those of the previous investigations of Mohammed et al (2021) .…”

“…The results revealed that all the extracts had inhibitory activity against Gram-positive and Gram-negative bacteria, with the exceptions of K. pneumoniae , Enterococcus faecalis , and S. aureus , which showed these bacteria, were resistant to A. nilagirica extracts. In research by Hussain et al (2022) , it was shown that A. rutifolia extracts in methanol, ethyl acetate, and n -hexane are rich in flavonoids and phenols, and that all of the studied extracts effectively inhibited the development of both Gram-positive and Gram-negative bacteria across a broad spectrum.…”

“…The results revealed that the n -hexane extract of A. parviflora showed a high level of antimicrobial activity for all the microbes tested with the MIC value of 32–64 mg/ml. Methanol and ethyl acetate extracts of A. parviflora showed moderate antimicrobial activity, due to the presence of higher concentrations of active antimicrobial agents such as terpenoids, phenolics, and volatile oils, in Artemisia species ( Hussain et al , 2022 ).…”

A phylogenetic perspective of antiviral species of the genus Artemisia (Asteraceae-Anthemideae): A proposal of anti SARS-CoV-2 (COVID-19) candidate taxa

“…Flavonoids are natural compounds linked by three carbon chains, usually C6-C3-C6, and consist of an oxygenated heterocyclic ring ( Xiao, 2017 ). Among the different plant sources containing flavonoids, the genus Artemisia is very diverse and widely distributed ( Hussain et al, 2022 ). In a study, the total number of phenols and flavonoids identified was 32 in A. annua, 37 in Artemisia iwayomogi Kitam., and 14 in Artemisia argyi H.Lév.…”

“…Abundant secondary metabolites retrieved from Artemisia extracts are used to treat certain health problems, such as stress, anxiety, depression, epilepsy, irritability, insomnia, and psychoneurosis ( Walter et al, 2003 ). Many Artemisia species are reported with antimalarial, antibacterial, antirheumatic, antiseptic, antispasmodic, hepato-protective, antitumor ( Terra et al, 2007 , Koul and Taak, 2017 , Hussain et al, 2017 , Pandey and Singh, 2017 , Hussain et al, 2022 , Mohammed et al, 2021 and references therein), antidiabetic ( Dabe and Kefale, 2017 ), antioxidant, cytotoxic ( Madhav et al, 2018 , Cheraif et al, 2020 , Jakovljevi´c et al, 2020 , Melguizo-Melguizo et al, 2020 ) and antiviral activities ( Li et al, 2005 , Romero et al, 2006 , Efferth et al, 2008 , Kim et al, 2018 , Nie et al, 2021 and references therein). It is believed that compounds extracted from the plants are responsible for antimicrobial activity and, in the former inquiries, various other biological activities have also been validated ( Mathlouthi et al, 2018 , Mathlouthi et al, 2021 ).…”