Phytochemicals toward Green (Bio)sensing

Abstract

Because of numerous inherent and unique characteristics of phytochemicals as bioactive compounds derived from plants, they have been widely used as one of the most interesting nature-based compounds in a myriad of fields. Moreover, a wide variety of phytochemicals offer a plethora of fascinating optical and electrochemical features that pave the way toward their development as optical and electrochemical (bio)sensors for clinical/ health diagnostics, environmental monitoring, food quality control, and bioimaging. In the current review, we highlight how phytochemicals have been tailored and used for a wide variety of optical and electrochemical (bio)sensing and bioimaging applications, after classifying and introducing them according to their chemical structures. Finally, the current challenges and future directions/perspective on the optical and electrochemical (bio)sensing applications of phytochemicals are discussed with the goal of further expanding their potential applications in (bio)sensing technology. Regarding the advantageous features of phytochemicals as highly promising and potential biomaterials, we envisage that many of the existing chemical-based (bio)sensors will be replaced by phytochemical-based ones in the near future.

Noncovalent Assembly Enabled Strong yet Tough Materials with Room-Temperature Malleability and Healability

“…Based on the GA-assisted sonication technique, bulk eutectic gallium indium (EGaIn), which has a melting temperature of 15 °C, , can be successfully shaped into nanosized droplets. During sonication, multiple reactions on GA molecules are performed. , The cavitation bubbles that result from high-frequency ultrasonication can function as the site of catalytic binding for the radical-mediated C–C phenol based-coupling. Oligomeric phenolic systems were formed by simple phenolic molecules via a C–C linakage, which occurs at the interface between the bubble and the solution (step 1).…”

BioAIEgens Derived from Rosin: How Does Molecular Motion Affect Their Photophysical Processes in Solid State?

“…Natural product-derived compounds are one of the most significant bioactive nature-based compounds due to their natural availability, renewability, sustainability, biodegradability, and biocompatibility compared to the pure artificial chemicals. 22 Among them, rosin is a renewable and sustainable natural resource, which is nevertheless limited to low value-added applications in current industry. In order to add high values of the rosin-derived biomaterials, we have herein succeeded a new class of BioAIEgens from the abundant and low-cost natural rosin via facile Schiff base reactions.…”

“…Alternatively, plantoriginated chemicals are green and bioactive compounds that have been widely studied as one of the most interesting naturebased compounds in the advanced (bio)sensing fields because of their numerous inherent and unique characteristics, such as natural availability, renewability, sustainability, biodegradability, and biocompatibility. 22 Hence, AIEgens from natural resources have recently gained researchers' intense attention (Figure S1). [23][24][25][26][27][28][29][30][31][32] To date, some natural product-based AIEgens including natural polymers (sodium alginate and bovine serum albumin) and small molecules (quercetin, myricetin, and berberine chloride) have been investigated with unique advantages in bioapplications.…”

A curcumin-based AIEE-active fluorescent probe for Cu2+detection in aqueous solution

“…It has been reported that curcumin derivatives usually have good coordination capability with Cu 2+ . 28 In the experimental process, only L1 has rapid uorescence response to Cu 2+ in L1-4. The uorescence intensity of L1 in different THF/water mixtures was tested before and aer adding one equivalent of Cu 2+ .…”