Phytochemicals and The Ability of Plantago major Linn. Extract to Inhibit The growth of Aeromonas hydrophila

Dewi, Annisa Farhana; Prajitno, Arief; Yuniarti, Ating

doi:10.21776/ub.jels.2019.009.02.02

Cited by 8 publications

(4 citation statements)

References 10 publications

(11 reference statements)

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“…The spectrum of the extract shows a broad band at 3275 cm -1 which is characteristic of the vibrations of phenolic groups and O-H bonds of polyphenols and flavonoids. It was also observed the presence of a band at 1719 cm -1 due to C=O bond also present in polyphenols and flavonoids of the P. major extract [35,60,61]. A characteristic band of P. major at 1558 cm -1 was observed in the FTIR spectra of PCL_5.3 and PCL_10.6 samples, demonstrating the incorporation of P. major extract in the polymer nanofibers [62][63][64].…”

Section: Fourier Transformation Infrared -Ftirmentioning

confidence: 98%

Functional Electrospun Nanofibers Loaded with Plantago Major L. Extract for Potential Use in Cutaneous Wound Healing

Mancipe¹,

Queiroz²,

Santos³

et al. 2023

Preprint

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Plantago major L. is a worldwide available plant that has been used traditionally for several medical application due to its properties such as wound healing, anti-inflammatory, antimicrobial etc. This work aimed to develop and evaluate nanostructured PCL electrospun dressing with P. major extract encapsulated in nanofibers for application in wound healing. The extract from leaves was obtained by extraction in a mixture of water:ethanol= 1:1 of the freeze-dried extract presented a minimum inhibitory concentration (MIC) for Staphylococcus Aureus susceptible and resistant to methicillin of 5.3 mg/mL, a high antioxidant capacity, but a low content of total flavonoids. Electrospun mats without defects were successfully produced using two P. major extract concentrations based on MIC value. The extract incorporation in PCL nanofibers was confirmed by FTIR and contact angle measurements. The PCL/P. major extract was evaluated by DSC and TGA demonstrating that incorporation of the extract decreases the thermal stability of the mats as well as the degree of crystallinity of PCL-based fibers. The P. major extract incorporation on electrospun mats produced a significant swelling degree (more than 400%) and increased the capacity of adsorbing wound exudates and moisture, important characteristics for skin healing. The extract-controlled release evaluated by in vitro study in PBS (pH, 7.4) shows that P. major extract delivery from the mats occurs in the first 24 h, demonstrating their potential capacity to be used in wound healing.

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Section: Fourier Transformation Infrared -Ftirmentioning

confidence: 98%

Functional Electrospun Nanofibers Loaded with Plantago Major L. Extract for Potential Use in Cutaneous Wound Healing

Mancipe¹,

Queiroz²,

Santos³

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Flavonoids belong to the promising groups of bioactive compounds with strong antioxidant and antiinflammatory properties [36]. In terms of benefits, flavonoids have antibacterial properties because they can release transduction energy to the bacterial cytoplasmic membranes and inhibit the mobility of bacteria [92]. They work by denaturing proteins so that the metabolic activity of bacterial cells stops [93].…”

Section: Ultrasonicationmentioning

confidence: 99%

A mini-review of bio-scrubber derived from bacterial cellulose impregnated by flavonoid of moringa leaves

Sa’adah

Milyawan

Nadya

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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Scrubber is widely used in various products, such as cosmetics, facial cleansers, and soaps. The use of scrubber releasing 209.7 trillion microplastics would harm the environment due to lack of process in treatment facilities. Efforts to substitute plastic-based scrubbers with more environmentally friendly materials need to be made. In previous studies, substitution scrubber with grape seeds has been done but has a low viscosity. This problem may be solved by using bacterial cellulose (BC) in the manufacture of bio-scrubbers. Several methods are currently being investigated to produce bacterial cellulose microparticles, such as mechanical methods using high-pressure homogenizer (HPH), acid hydrolysis, microbial hydrolysis, hydrogel fiber cultivation, microfluidic process, and ultrasonication. This review recommends the manufacture of bacterial cellulose microparticles by ultrasonication method. The recommendation is based on the literature study that has been carried out. The ultrasonication method has more advantages than other methods. It does not use solvents that pollute the environment and increasing the number of bacterial cellulose microparticles. The synthesis of bio-scrubber from bacterial cellulose ends with the drying process of bacterial cellulose microparticles. This review recommends the ambient pressure drying method. The ambient pressure drying method can produce bio-scrubber with high crystallinity, high mechanical properties, and transparency.

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“…Ketika metabolisme proses terhambat, pertumbuhan dan perkembangan bakteri akan terhambat. 34 Mekanisme kerja alkaloid sebagai antibakteri yaitu dengan cara menghambat komponen penyusun peptidoglikan pada sel bakteri yang menyebabkan dinding sel tidak terbentuk utuh sehingga dapat menyebabkan kematian sel, sedangkan mekanisme kerja terpenoid adalah dengan cara merusak membran sel.…”

Section: Andalas Dental Journalunclassified

Efektivitas Antibakteri Ekstrak Biji Alpukat (Persea americana Mill.) terhadap Pertumbuhan Bakteri Streptococcus mutans

Sholekhah,

Hidayati,

Kustantiningtyastuti

2022

Andalas Dent. J.

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Background : Streptococcus mutans bacteria are the main microorganisms that play an important role in the etiology of caries. Prevention of dental caries can be done by reducing the formation of plaque on the surface of the teeth, one of which is through the use of antibacterial compounds contained in avocado seed extract. Purpose : This study is to determine the antibacterial effectiveness of avocado seed extract in inhibiting the growth of Streptococcus mutans bacteria. Methods : This research method is an experimental laboratory with a post-test control group design. The avocado seed extract is made with a maceration technique with the result of a concentration of avocado seed extract of 100% then diluted using aquadest so that avocado seed extract concentrations of 10%, 15%, 20%, and 25% are obtained. The inhibitory test was done by Kirby-Bauer disk diffusion on Mueller Hinton Agar. The inhibition zone formed around the disc is measured using a caliper. The data analysis used was the One Way Anova test and continued with the Post Hoc LSD test. Results : The results showed that avocado seed extract at all concentrations can inhibit the growth of Streptococcus mutans bacteria. The largest inhibitory zone diameter at a concentration of 25% with a diameter of 12.25 mm and the diameter of the smallest inhibitory zone at a concentration of 10% at 10.48mm. the results of statistical analysis showed that there were significant differences between the inhibition zones of each avocado seed extract concentration (p<0.05).Conclusions : there is an effect of avocado seed extract (Persea americana Mill.) in inhibiting the growth of Streptococcus mutans bacteria with extract concentrations of 10%, 15%, 20%, and 25%.

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Phytochemicals and The Ability of Plantago major Linn. Extract to Inhibit The growth of Aeromonas hydrophila

Cited by 8 publications

References 10 publications

Functional Electrospun Nanofibers Loaded with Plantago Major L. Extract for Potential Use in Cutaneous Wound Healing

Functional Electrospun Nanofibers Loaded with Plantago Major L. Extract for Potential Use in Cutaneous Wound Healing

A mini-review of bio-scrubber derived from bacterial cellulose impregnated by flavonoid of moringa leaves

Efektivitas Antibakteri Ekstrak Biji Alpukat (Persea americana Mill.) terhadap Pertumbuhan Bakteri Streptococcus mutans

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