Phytochemical studies of the flowers of Pterospermum acerifolium

Rizvi, S. A. I.; Sultana, Tajwar

doi:10.1016/0031-9422(72)80076-1

Cited by 10 publications

(2 citation statements)

References 7 publications

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“…8 In flowers, 24 b-ethylcholest-5-en-3beta-0-alpha-cellobiside, b-amyrin, b-sitosterol, n-triacontanol, nhexacosane-1-26-diol dilignocerate and a mixture of acids and saturated hydrocarbon were isolated from the light petroleum ether extract of the dried flowers. 9 In addition to that, 4 0 -(2-methoxy-4-(1,2,3-trihydroxypropyl) phenoxy) luteolin, 5,7,3 0 -trihydroxy-6-Ob-D-glucopyranosyl flavone, 3,5-dihydroxyfuran-2(5H)-one 10 kaempferol and kaempferide-7-glucoside were isolated from the alcoholic extracts of the dried flowers. 11 From barks, D-galacturonic acid, D-galactose and alpha-rhamnose in the molar ratio 5:3:3 were isolated.…”

Section: Introductionmentioning

confidence: 98%

Evaluation of antioxidant and DNA nicking potential along with HPTLC fingerprint analysis of different parts of Pterospermum acerifolium (L.) Willd

Rathinavelusamy

Mazumder

Sasmal

et al. 2013

Free Radicals and Antioxidants

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Objective: The present study was designed to evaluate the in vitro antioxidant and DNA nicking potential of various extracts and fractions of Pterospermum acerifolium (L.) Willd (Family: Stericuliaceae). Research design and methods: Antioxidant properties of the extracts and fractions was assayed by DPPH scavenging activity, non-site-specific and site-specific OH radical scavenging activity mediated 2-deoxy-D-ribose degradation, total antioxidant activity and lipid peroxidation assay by using rat liver homogenate. DNA nicking assay was studied by PT257R/T plasmid. Estimation of total phenolic content and total flavonoid content was done. Further HPTLC fingerprint of active fractions was performed. Results: Ethyl acetate fractions of leaves, flowers and bark exhibited potent antioxidant property and DNA protective effect compare to all the other extracts and fractions. Total phenolic and flavonoid content determination was also showed ethyl acetate fractions were rich in phenolic and flavonoid contents. HPTLC fingerprint revealed the total number of peaks present in the active ethyl acetate fractions of leaves, flowers and bark. Conclusion: The present study indicated that, ethyl acetate fractions of leaves, flowers and bark showed effective antioxidant and DNA protection activity and it could be the initiation for various other pharmacological studies on those fractions.

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Section: Introductionmentioning

confidence: 98%

Evaluation of antioxidant and DNA nicking potential along with HPTLC fingerprint analysis of different parts of Pterospermum acerifolium (L.) Willd

Rathinavelusamy

Mazumder

Sasmal

et al. 2013

Free Radicals and Antioxidants

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“…Immunomodulation using medicinal plants is seriously being considered as an alternative approach to conventional chemotherapy for treatment of various diseases (Ganju et al, 2003). Pterospermum acerifolium (PA) wild (Sterculiaceae) is a shrub distributed in India and found particularly in sub-Himalayan tract, outer Himalayan valley and hills up to 4000 ft (Rizvi and Sultan, 1972). The plant is commonly known as Kanakchampa, Karnikara, Muchukunda and Matsakanda.…”

Section: Introductionmentioning

confidence: 99%

Immunosuppressive activity of hexane and ethanolic extracts of Pterospermum acerifolium seeds in BALB/c mice

et al. 2010

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The hexane and ethanolic extracts prepared from the seeds of plant Pterospermum acerifolium were evaluated for their immunomodulatory activities by exploiting their effects on the humoral and cellular immune arms of BALB/c mice after oral administration for 14 consecutive days at different log doses. Various immune parameters viz. lymphoproliferative index, oxidative burst in peritoneal macrophages, modulation in T/B cell population and regulation of Th1/Th2 cytokines in mice were monitored to assess the immunomodulatory characteristics of the plant at 3, 10 and 30 mg/kg doses. Both the extracts exerted remarkable dose-dependent immunosuppressive effect with down-regulation of all the immune markers studied. Administration of extracts in immune-stimulated mice (by treatment with levamisole) further validated the immunosuppressive action. The findings are exceedingly encouraging and warrant bioactivity guided fractionation/ purification to locate the activity in a single molecule for its future use in autoimmune disorders and organ transplant patients.

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Sterculiaceae

Hegnauer

1973

Chemotaxonomie Der Pflanzen

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Phytochemical studies of the flowers of Pterospermum acerifolium

Cited by 10 publications

References 7 publications

Evaluation of antioxidant and DNA nicking potential along with HPTLC fingerprint analysis of different parts of Pterospermum acerifolium (L.) Willd

Evaluation of antioxidant and DNA nicking potential along with HPTLC fingerprint analysis of different parts of Pterospermum acerifolium (L.) Willd

Immunosuppressive activity of hexane and ethanolic extracts of Pterospermum acerifolium seeds in BALB/c mice

Sterculiaceae

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