Phytochemical Screening, Toxicity Evaluation of Polycarpaea Corymbosa Lamk and Its Effect on Cancer Biomarkers of Ehrlich Ascites Carcinoma-Induced Mice Compared With the Reference Standard Drug 5- Fluorouracil
Abstract:Objective: The current investigation focuses on the study of efficacy of whole plant of Polycarpaea corymbosa Lamk in Ehrlich ascites carcinoma (EAC) inoculated Swiss albino mice.
Methods: The whole plant of P. corymbosa Lamk (WPC) was extracted with solvents of increasing polarity and their percentage yields were calculated. The major phytoconstituents present in the plant extracts were determined by standard chemical tests. Tumor was induced in mice by intraperitoneal injection of EAC cells (1×106 cells/mous… Show more
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