Phytochemical Screening of the Ethanol and Aqueous Extracts of Dicliptera verticillata Leaves

Akpakpan, Aniekan E.; Ukpong, Etiowo George; Odiongenyi, Anduang O.; Willie, Itoro E.

doi:10.9734/acri/2017/29722

Cited by 5 publications

(3 citation statements)

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“…The decrease in total cholesterol levels in the group administered ethanol extract was larger compared with the group administered the ethyl acetate fraction. Compounds contained within the ethanol extracts include flavonoids and saponins ( 32 ). Saponin binds with cholesterol and bile to form strong complex compounds and cannot be reabsorbed ( 33 , 34 ).…”

Section: Discussionmentioning

confidence: 99%

Isolation and identification of a flavonoid compound and in vivo lipid‑lowering properties of Imperata cylindrica

et al. 2020

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Cogon grass (Imperata cylindrica/I. cylindrica) of the Gramineae family is found abundantly in nature, and the roots of this plant possess several beneficial biological properties. The present study aimed to isolate and identify flavonoid compounds from cogon grass roots and examine their potential as hypocholesterolemic agents. The flavonoid compound was isolated using a maceration method, followed by gravity column chromatography until a pure compound was obtained. The molecular structure of the isolated compound was determined using 1 H-nuclear magnetic resonance (NMR) and 13 C-NMR spectroscopy. An in vivo lipid-lowering test used a randomized post-test only control group experimental design in rats with hypercholesterolemia. The animals were divided into four groups: K0, negative control; K1, positive control; K2, ethanol extract treated group; and K3, ethyl acetate fraction treated group, and the lipid profiles were examined at the end of the study. The isolated compound, 7,3' ,5'-trimethoxyflavonol, was collected in yellow powder form; was shown to be a flavonoids and was comprised of 18 carbon atoms and 16 hydrogen atoms. In vivo tests demonstrated that 15 mg/200 g body weight (BW) of an ethanol extract significantly lowered total cholesterol levels (P= 0.001) but did not lower low-density lipoprotein (LDL) (P= 0.109) and high-density lipoprotein (HDL) levels (P=0.003). The fraction of ethyl acetate administered at 15 mg/200 g BW was capable of lowering the total cholesterol levels significantly (P=0.002) and lowered LDL levels (P=0.006) but was unable to increase HDL levels (P=0.190). The in vivo tests showed that the ethyl acetate fraction of I. cylindrica reduced total cholesterol and LDL levels more effectively than the ethanol extract, but did not affect HDL levels in rats with hypercholesterolemia.

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Section: Discussionmentioning

confidence: 99%

Isolation and identification of a flavonoid compound and in vivo lipid‑lowering properties of Imperata cylindrica

et al. 2020

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“…It is also used as flavouring and spicing agent" [8]. "The phytochemical constituents of the ethanol and aqueous extracts of this plant leaves" have been reported by Akpakpan et al, [9]. The plant contains several phytochemicals which can enhance colour changes during acidbase titration.…”

Section: Introductionmentioning

confidence: 97%

UV/visible Spectroscopic Studies and Analytical Evaluation of Dicliptera verticillate Leaves Extracts as Eco-friendly Indicator for Acid-Base Titration

Nsi

Akpakpan

Uwanta

et al. 2022

AJACR

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Synthetic indicators usually employed in acid-base titration to determine the end point is expensive and non-biodegradable. Hence there is need to develop an eco-friendly and cost effective acid-base indicator from plant origin to serve as efficient alternative for the synthetic indicators. This research work focused on the development of easily available, cost effective and eco-friendly indicator from Dicliptera verticillate leaves extracts for acid-base titration. UV/visible spectrometer was used to analyzed the ethanol extract (EE), ethanol extract in basic medium (EEB), ethanol extract in acidic medium (EEA), hot water extract (HWE), Hot water extract in basic medium (HWEB) and hot water extract in acidic medium (HWEA) to determine the wavelength of maximum absorption (λmax), and the absorbance of the extracts in different media in order to evaluate the chromophoric properties of the plant extracts phytochemicals before and after titrations. Titrimetric analysis was carried out in the reactions of strong acid/strong base (HCl/NaOH), strong acid/weak base (HCl/NH4OH), weak acid/strong base (CH3COOH /NaOH) and weak acid/weak base (CH3COOH/NH4OH). The results revealed that both extracts exhibit hypsochromic shift (shift to a shorter wavelength) with corresponding hypochromic effect (decreased in the absorption intensity) in both acidic and basic media. The titrimetric results revealed that the plant extracts give the end point comparable to that of the synthetic indicators such as methyl orange and phenolphthalein. Hence ethanol and hot water extracts of Dicliptera Verticillate can be utilized as suitable alternative indicators for acid - based titrations, since it is biodegradable and cost effective.

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“…Canned green jackfruit has a mild taste, and the pulp has a meat-like texture, earning it the label of "vegetable meat" (Ong et al, 2006). Phytochemicals, which is a bio-active chemicals components of plants, are considered as secondary metabolites, synthesized naturally in all parts of the plant body (Akpabio et al, 2012a;Akpakpan et al, 2017). Hence, any part of the plant body may contain these bioactive components.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening, proximate and vitamin composition of Jack fruit (Artocarpus Heterophyllus) pulp and seed

Emaime Jimmy Uwanta,

Itoro Eshiet Udo,

Itoro Nyakno Willie

et al. 2024

World J. Adv. Res. Rev.

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The potential health benefits of plant are determined by the level of phytochemicals, proximate, minerals and vitamin composition of the plant material. The study was carried out to determine the phytochemical composition, proximate and vitamin content of Artocarpus heterophyllus pulp and seeds. The results revealed that Artocarpus heterophyllus is rich in phytochemicals such as Saponins, Alkaloid, Cardiac Glycoside, Phlobatannins, Terpenes, Steroids and Deoxy-Sugar. Proximate composition analysis indicated that the pulp has higher moisture, protein and lipid content, while crude fibre and carbohydrate were higher in the seed. The fruit pulp contained a greater percentage of vitamins A and C compared to the seeds. These phytochemicals, proximate composition, and vitamins offer numerous health benefits, suggesting that the consumption of jack fruit pulp and seeds may help in alleviating various health challenges.

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Phytochemical Screening of the Ethanol and Aqueous Extracts of Dicliptera verticillata Leaves

Cited by 5 publications

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Isolation and identification of a flavonoid compound and <em>in vivo</em> lipid‑lowering properties of <em>Imperata cylindrica</em>

Isolation and identification of a flavonoid compound and <em>in vivo</em> lipid‑lowering properties of <em>Imperata cylindrica</em>

UV/visible Spectroscopic Studies and Analytical Evaluation of Dicliptera verticillate Leaves Extracts as Eco-friendly Indicator for Acid-Base Titration

Phytochemical screening, proximate and vitamin composition of Jack fruit (Artocarpus Heterophyllus) pulp and seed

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Phytochemical Screening of the Ethanol and Aqueous Extracts of Dicliptera verticillata Leaves

Cited by 5 publications

References 0 publications

Isolation and identification of a flavonoid compound and <em>in&nbsp;vivo</em> lipid‑lowering properties of <em>Imperata&nbsp;cylindrica</em>

Isolation and identification of a flavonoid compound and <em>in&nbsp;vivo</em> lipid‑lowering properties of <em>Imperata&nbsp;cylindrica</em>

UV/visible Spectroscopic Studies and Analytical Evaluation of Dicliptera verticillate Leaves Extracts as Eco-friendly Indicator for Acid-Base Titration

Phytochemical screening, proximate and vitamin composition of Jack fruit (Artocarpus Heterophyllus) pulp and seed

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Isolation and identification of a flavonoid compound and <em>in vivo</em> lipid‑lowering properties of <em>Imperata cylindrica</em>

Isolation and identification of a flavonoid compound and <em>in vivo</em> lipid‑lowering properties of <em>Imperata cylindrica</em>