Phytochemical screening and In Vitro Antioxidant potential of Memecylon umbellatum Burm leaf extracts

Abstract

Objective: Different dry extracts of Memecylon umbellatum Burm leaf obtained by various solvents such as petroleum ether, chloroform, ethyl acetate, acetone, methanol and chloroform water (IP) was screened to reap the benefits of its antioxidant and free radical scavenging properties using ascorbic acid as standard antioxidants. Methods: The in vitro free radical scavenging activity was evaluated using diphenyl picryl hydrazyl (DPPH) radical method using various concentrations of dry extract in distilled water (1, 2, 4, 8, 16, 20 μg/ml) against blank with ascorbic acid as a standard in same concentrations. Results: Among the all extracts, Methanol leaf extract has showed higher Antioxidant activity (84.65 ± 0.064 %) having IC 50 Value 11.81 ± 0.033 μg/ml at 20 μg/ml. While, IC 50 value for ascorbic acid was found to be 8.91 ± 0.084 μg/ml. Conclusion: The results clearly indicate that Methanol leaf extract of Memecylon umbellatum is effective in free radical scavenging. So in future, this may emerge as promising natural herbal source of powerful antioxidant.

In vitroevaluation of antioxidant, antiproliferative potentials of bioactive extract-cum-rutin compound Isolated fromMemecylon eduleleaves and its molecular docking study

“…This variation in IC 50 values is due to the extraction solvents and methods 27 . Several plants belonging to Memecylon genus namely, M. teminale 30 , M. umbellatum 31,32 , M. umbellatum, M. talbotianum, M. malabaricum 33 and thirty two Memecylon species 28 were studied for their antioxidant potential on different free radicals which strengthen the outcome of the present investigation. 33.88 ± 0.14 *-The values are mean of triplicates with (±) standard deviation (mean ± S.D; n=3).…”

In vitro inhibitory activities of selected Australian medicinal plant extracts against protein glycation, angiotensin converting enzyme (ACE) and digestive enzymes linked to type II diabetes

“…Other Memecylon species used in traditional medicine in India including those reported as Memecylon umbellatum , M. talbotianum, M. edule and M. malabaricum have been studied for their medicinal effects including antioxidant [56, 57], anti-inflammatory [58, 59] and in vivo antidiabetic effects [60]. …”

Antimicrobial and Antioxidant Activity Analysis of Some Medicinal Plants of Bangladesh

“…1 Antimicrobial and antioxidant properties in the leaves of Memecylon umbellatum Burm., have been used to treat many diseases and physiological disorders like leucorrhoea and gonorrhea. [12][13][14][15] Wound healing activity of ethanolic extract of the leaves has also been reported. 16 Equisetum debile is administered as a cooling medicine which is well known to be used for the remediation of nasal polypus, various cancers of breast, liver, intestine, stomach, kidneys and tongue.…”