2019
DOI: 10.22270/jddt.v9i1.2174
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Phytochemical screening and GC–MS analysis of bioactive compounds present in ethanolic leaves extract of Silybum marianum (L).

Abstract: Objective: To investigate the phytochemicals and GC-MS analysis of ethanol extracts of Silybum marianum. Methods: The air-dried leaves were powdered and subjected to selective sequential extraction using solvents of increasing polarity through percolation, ethanol to obtain an ethanolic extract. Then, each of the extracts was further subjected to gas chromatography-mass spectrometry. Results: Qualitative determination of the different biologically active compounds from crude extracts of Silybum marianum using … Show more

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Cited by 38 publications
(19 citation statements)
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“…The concentration of silymarin is organ-dependent, and it is only localized in the outer portion of the fruit, which includes all the cell layers from the pericarp epidermis to the albumen, and embryos [6], accounting for 1.5-4.3% of the fruit weight [7]. Silymarin is not present in flowers, stems, or leaves, and it is not found in steps before the development of fruit [8,9], which explains why other milk thistle plant organs have been scarcely investigated for bioactive compounds: total polyphenol and flavonoid contents in leaves' extracts were studied by Saidi, et al [10]; a phytochemical screening and gas chromatography-mass spectrometry (GC-MS) analysis of bioactive compounds present in ethanolic leaves extract was conducted by Mani, et al [11]; and Sulas, et al [12] studied the concentrations of crude protein, fat, total phenolics, and total flavonoids in leaves, heads, and stems.…”
Section: Introductionmentioning
confidence: 99%
“…The concentration of silymarin is organ-dependent, and it is only localized in the outer portion of the fruit, which includes all the cell layers from the pericarp epidermis to the albumen, and embryos [6], accounting for 1.5-4.3% of the fruit weight [7]. Silymarin is not present in flowers, stems, or leaves, and it is not found in steps before the development of fruit [8,9], which explains why other milk thistle plant organs have been scarcely investigated for bioactive compounds: total polyphenol and flavonoid contents in leaves' extracts were studied by Saidi, et al [10]; a phytochemical screening and gas chromatography-mass spectrometry (GC-MS) analysis of bioactive compounds present in ethanolic leaves extract was conducted by Mani, et al [11]; and Sulas, et al [12] studied the concentrations of crude protein, fat, total phenolics, and total flavonoids in leaves, heads, and stems.…”
Section: Introductionmentioning
confidence: 99%
“…Hydrocarbon Antimicrobial activity [15] Bornanone Terpene Anti-inflammatory, antifungal, antimicrobial, anticancer [15] αpinene, β-pinene, sabinene, myrecene, β-ocimene Monoterpenes Antimicrobial, antifungal, antioxidants [16] Eucalyptol, citronelal, eucamalol, linalool, α-terpineol Alcohols Antioxidant, insecticide, acaricide, herbeside [17] Bisabolane, elemane, germacrane, humulane, chamazulene Sesquiterpenes Antibacterial, antifungal, antiinflammatory, antioxidant [18] Cinnanaldehyde, benzaldehyde, myrtenal Aldehyde Antifungal, circulatory, antiinflammatory, cardiovascular [19] Geranyl acetate, bornyl acetate, linalyl acetate, eugenol acetate Ester Antispasmodic, antimicrobial [20] Pulegone, fenchone, thujone Ketone Antiviral, gastrointestinal, regenerating cells, analgesic [21] Carvacrol, tymol Phenol Antibacterial, strengthening immune system [22] Table 1.…”
Section: Dodecane Phellandrenementioning
confidence: 99%
“…Be that as it may, little data is accessible about the potential danger of certain restorative plants for human wellbeing, albeit many contain synthetic substances known to be mutagenic and/or cancer-causing. Other than the ease, they are found in incredible assortment in our nation local species that are utilized exactly for centuries [25]. Natural products are subtle, not conspicuous, under 0.5 inch, and green-shaded.…”
Section: Antioxidant Activitymentioning
confidence: 99%