Phytochemical screening and evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn. aerial parts

Sarkar, Kishore Kumar; Mitra, Trina; Acharyya, Rabindra Nath; Sadhu, Samir Kumar

doi:10.1007/s13596-018-0357-3

Cited by 22 publications

(20 citation statements)

References 30 publications

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“…This mediators are known to be accountable for pain sensation. 22 In the analgesic activity evaluation, A. corniculatum extract showed significant inhibition of writhing impulse, by 54.78% and 75.60% at 250 mg/kg and 500 mg/kg b.w. doses, respectively.…”

Section: Resultsmentioning

confidence: 95%

“…Brine shrimp lethality bioassay was performed on Artemia salina nauplii in order to investigate the cytotoxic activity of the A. corniculatum extract according to the method of Sarkar et al 22 At first, the eggs of A. salina were hatched for nauplii. Solution of different concentrations of plant extract (5, 10, 20, 40, 80, 160, 320, 640 μg/mL) and standard (10, 5, 2.5, 1.25, 0.625, 0.3125, 0.1562 μg/mL) were prepared by serial dilution.…”

Section: Brine Shrimp Lethality Bioassaymentioning

confidence: 99%

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Phytochemical Characterization and Evaluation of Pharmacological Activities of Leaves of a Mangrove Plant Species - Aegiceras corniculatum (L.)

2020

TJNPR

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Medicinal plants may be defined as a group of plants that possess some special properties which qualify them as drugs or therapeutic agents and are used for medicinal purposes. 1 Even with the advent of technologies like combinatorial chemistry or computeraided drug design, medicinal plants containing bioactive chemical constituents are extensively responsible for the development of new drugs. 2 Molecules containing one or more unpaired electrons are called free radicals. In our body during the normal oxidation of foods, free radicals are constantly generated and about 1-4% of oxygen taken up in the body is converted to free radicals by oxidase enzymes. 3 For these free radicals, lipid peroxidation occurs which is responsible for the oxidation of sulfhydryl groups, protein deformation, DNA bases fragmentation which can result in the mutation of genetic sequences. Free radicals cause different diseases such as cancer, inflammation, respiratory and cardiovascular disorder, muscular dystrophy, diabetes and neurological disorder. 4 To neutralize these free radicals, antioxi

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Section: Resultsmentioning

confidence: 95%

Section: Brine Shrimp Lethality Bioassaymentioning

confidence: 99%

Phytochemical Characterization and Evaluation of Pharmacological Activities of Leaves of a Mangrove Plant Species - Aegiceras corniculatum (L.)

2020

TJNPR

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“…These free radicals are responsible for causing different types of pernicious effects to our body such as lipid peroxidation, stimulating oxidation of sulfhydryl groups and then leading to bind to our cellular components. As a result, these further lead to different diseases such as atherosclerosis, muscular dystrophy, inflammation, cancer, diabetes and different types neurological, cardiovascular and respiratory disorders [15] . To combat these free radicals associated damages, antioxidants play a very crucial role.…”

Section: Resultsmentioning

confidence: 99%

Investigation of phytochemical and pharmacological assessment of ethanol extract of <em>Stenochlaena palustris</em>- an edible fern of Sundarbans

Debnath¹,

Kundu²,

Ahad³

et al. 2021

J. Med. Plants Stud.

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Stenochlaena palustris is a widely found fern in mangrove forests and other areas of different countries over the world. This plant has many uses in traditional medicine of many countries. This study was conducted on its leaves extract to investigate its different phytochemical and pharmacological properties based on its local medicinal uses. Phytochemical screening indicated the presence of different secondary metabolites in this plant. On silica coated TLC plates, the extract exhibited the presence of different antioxidative compounds. Total phenolic, flavonoid and tannin contents were determined (97 mg GAE/g, 90 mg QE/g and 23 mg GAE/g, respectively). This extract also scavenged DPPH, hydrogen peroxide and superoxide radicals (SC50 = 80, 158 and 236 μg/ml, respectively). It also showed ferric ion reducing capability (RC50 =166 μg/ml). This plant showed significant antihyperglycemic, peripheral analgesic (acetic acid induced), anti-inflammatory (formaldehyde induced) and laxative activities in mice. This plant also showed little cytotoxic activity in brine shrimp lethality bioassay. These results are also compared with respective standard drugs and our findings justified its traditional usage.

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“…Qualitative screening of a number of phytochemical groups such as alkaloids, glycosides, tannins, saponins, phenolics, flavonoids, carbohydrates, acidic compounds, steroids, gums, and anthraquinones was performed for both extracts. 12…”

Section: Qualitative Phytochemical Screeningmentioning

confidence: 99%

Evaluation of Pharmacological Activities of Fractionated Extracts of Hoya parasitica Wall. Leaves

2021

TJNPR

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Phytochemical screening and evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn. aerial parts

Cited by 22 publications

References 30 publications

Phytochemical Characterization and Evaluation of Pharmacological Activities of Leaves of a Mangrove Plant Species - Aegiceras corniculatum (L.)

Phytochemical Characterization and Evaluation of Pharmacological Activities of Leaves of a Mangrove Plant Species - Aegiceras corniculatum (L.)

Investigation of phytochemical and pharmacological assessment of ethanol extract of <em>Stenochlaena palustris</em>- an edible fern of Sundarbans

Evaluation of Pharmacological Activities of Fractionated Extracts of Hoya parasitica Wall. Leaves

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