Nepal is blessed with most varied and diverse soil and climate conditions suitable for the growth of veritable plant species. The indigenous people are well acquainted with the properties and uses of plants of their surroundings. Until the middle of the 19 th century, plants were the main therapeutic agents used by humans. About 60% of the world population and 60-90% of the population of developing countries rely on traditional medicine [3] and about 85% of the traditional remedies for primary health care are derived from plants. [4] In Nepal, at least 1,600 to 1,900 species of plants are commonly used in traditional medicinal practices. [5] Traditional medicine in Nepal is used extensively by majority of the population, and includes Ayurveda, Traditional Chinese medicine (TCM), Unani and various forms of indigenous medicine including Tibetan Amchi medicine. [6] Traditional medicine in Nepal comprises those practices based on beliefs that were in existence often for hundreds to thousands of years before the development and spread of modern medicine, and which are still in use today. In the past, many rural areas of Nepal, traditional medicinal knowledge and practice were passed down entirely via oral tradition based on a lineage mode of transmission and personal experience. [7] More recently, however, knowledge transfer has also occurred through formally recognized