Phytochemical profiling of Turbinaria ornata and its antioxidant and anti-proliferative effects

Abstract

Objectives To analyse the phytochemicals and evaluate the antioxidant and anti-proliferative ability of Turbinaria ornata (Turner) J. Agardh, 1848. Methods A phytochemical analysis of the T. ornata -hexane extract (To-HE) and T. ornata -aqueous extract (To-AE) was performed. T. ornata extracts were analysed by gas chromatography-mass spectrometry (GC-MS), Fourier transform infrared spectroscopy (FTIR) and high-performance liquid chromatography (HPLC). The antioxidant properties of To-HE and To-AE were determined by 2,2-diphenyl-1-picrylhydrazyl radical scavenging (DPPH) and ferric ion reducing power (FRAP) assays. In addition, the in vitro anti-proliferative properties of To-HE and To-AE were assessed in kidney epithelial cells from the African green monkey ( Vero ) and in adenocarcinomic human alveolar basal epithelial cells (A549) using the MTT (3-(4,5-dimethylthiazol- 2yl)-2,5-diphenyltetrazolium bromide, a yellow tetrazole) assay. Results The phytochemical screening of T. ornata revealed the presence of saponin, alkaloids, amino acids, fixed oil and fat and phenolic compounds (tannins, flavonoids and total phenol). A higher antioxidant ability was found in To-HE than in To-AE. The anti-proliferative efficacy values (μg/mL) of To-HE and To-AE for A549 and Vero cells were 62.91 and 93.00 and 72.64 and 106.6, respectively. The FTIR analysis revealed the presence of functional groups such as alcohols, amides, aromatics, amines, alkyl halides, alkynes, alkanes and carboxylic acids. The GC-MS analysis of To-HE revealed the presence of 13 active compounds. Conclusion Owing to its recorded anti-proliferative effect, further pharmaceutical studies on the development of this anticancer drug are merited.

Photocatalytic Degradation of Rhodamine B Dye Using Biogenic Hybrid ZnO‐MgO Nanocomposites under Visible Light

“…The absorption bands at 1629 cm −1 and 1048 cm −1 are attributed to the stretching vibration modes of ‐C=N and ‐C−O respectively. The strong absorption peaks at 1369–1459 cm −1 corresponds to aromatic ring alkane (=C−H) units . The strong broad bands at 517–548 cm −1 are assigned to metal oxide stretching and bending vibration modes, respectively.…”

Antifungal, Antibacterial and Antioxidant Components of Ethyl Acetate Extract of Quinoa Stem

“…On the other hand, the compounds present in less concentrations were phenol, 3-methyl (1), 1,2-benzenedicarboxylic acid, bis(2methylpropyl) ester (8), hexadecane (7), pentadecane (5), tetradecane (4) and 1-octadecanol (11) with peak areas ranging from 1.70 to 2.79%. The most abundant compound 13 was previously identified by Deepak et al (2017) from n-hexane extract of Turbinaria ornata and is known to possess antimicrobial properties against Bacillus subtilis, Escherichia coli, Aspergillus niger, Pseudomonas aeruginosa and Candida albicans. This compound is also known for its antiviral, antioxidant, anticancer and antiinflammatory properties.…”

Thermogravimetric Characteristics and Non-isothermal Kinetics of Macro-Algae With an Emphasis on the Possible Partial Gasification at Higher Temperatures

“…Red Sea seaweeds primarily consist of small green and brown algal filaments found in the northern and central parts, while the southern area of the Red Sea has large brown algal species like Sargassum and Turbinaria spp (Bruckner et al, 2013). Turbinaria ornata (T. ornata) is a well-known brown alga suitable for human consumption due to its antioxidant characteristics (Deepak et al, 2017a). Several studies have discussed its antibacterial, antioxidant, and anticancer properties (Omar et al, 2012;Ponnan et al, 2017;Stranska-Zachariasova et al, 2017;Tenorio-Rodriguez et al, 2017) as well as the biogenic synthesis of crystalline Ag/Au nanoparticles (Rajeshkumar et al, 2013;Kayalvizhi et al, 2014;Deepak et al, 2017b), but to the best of the authors' knowledge, no previous studies are available for its use as a source of biofuel.…”