Phytochemical profiling and bioactivity assessment of underutilized Symphytum species in comparison with Symphytum officinale
Simon Vlad Luca,
Gokhan Zengin,
Łukasz Kulinowski
et al.
Abstract:BACKGROUNDSymphytum (comfrey) genus, particularly Symphytum officinale, has been empirically used in folk medicine mainly for its potent anti‐inflammatory properties. In an attempt to shed light on the valorization of less known taxa, the current study evaluated the metabolite profile and antioxidant and enzyme inhibitory effects of nine Symphytum species.RESULTSPhenolic acids, flavonoids and pyrrolizidine alkaloids were the most representative compounds in all comfrey samples. Hierarchical cluster analysis re… Show more
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