Phytochemical Profile and Antiproliferative, Anti-tyrosinase, Antioxidant, and Antibacterial Potential of <i>Schinus terebinthifolius</i> Growing in Tunisia

Sassi, Ahlem Ben; ElAyeb, Asma; Karaman, İsa; Marzouk, Belsem; Mastouri, Maha

doi:10.1080/10496475.2019.1677277

Cited by 4 publications

(5 citation statements)

References 25 publications

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“…The DPPH and ABTS assays revealed that oil extract of Schinus terebinthifolius fruit has the highest radical scavenging activity, with an IC 50 value of 0.016 and 0.017 mg/mL, respectively, stronger than the Trolox (DPPH = 0.136 mg/mL; ABTS = 0.145 mg/mL). Other than that, both leaf and fruit methanol extract also exhibited promising radical scavenging activity, with IC 50 values of 0.53 and 0.41 mg/mL in the DPPH assay, as well as 0.76 and 0.61 mg/mL in the ABTS assay …”

Section: Biological Activitiesmentioning

confidence: 97%

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Searching for Natural Plants with Antimelanogenesis and Antityrosinase Properties for Cosmeceutical or Nutricosmetics Applications: A Systematic Review

Tung,

Yip,

Gew

2023

ACS Omega

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Excessive UV radiation (UVR) exposure has been shown in studies to be a major risk factor for most melanomas, causing premature skin aging as well as immune system suppression due to the increased production of hydrogen peroxide (H2O2) and other reactive oxygen species (ROS) during the melanogenesis process. Although several compounds with antioxidant and antityrosinase activities are widely used in the cosmetic industry, like kojic acid, hydroquinone, ascorbic acid, and arbutin, their use has been limited due to their adverse effects on the skin and cytotoxic issues. Recently, attempts have been made to develop new natural skin-lightening products by using plant extracts that are less toxic and exhibit numerous biological properties with great market demand. In this study, information on the depigmentation effects of various natural plant species was gathered from the SCOPUS database according to the PRISMA guidelines. A total of 414 records were retrieved, and finally, 76 articles were included in the qualitative synthesis by fulfilling all the inclusion criteria. In this review, we discuss the extraction methods and biological assays of 75 highly potential plant species, including the olive, yuzu, longan, and lotus. We concluded that the use of natural plants as skin-whitening agents is highly effective as there is a significant correlation between the content of polyphenolic compounds, antimelanogenesis, antityrosinase, and antioxidant activities. However, it is worth noting that the use of extraction methods or types of solvents is very important in determining the biological activities of plants.

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Section: Biological Activitiesmentioning

confidence: 97%

“…Other than that, both leaf and fruit methanol extract also exhibited promising radical scavenging activity, with IC 50 values of 0.53 and 0.41 mg/mL in the DPPH assay, as well as 0.76 and 0.61 mg/mL in the ABTS assay. 79 4.66. Schisandra chinensis (Turcz.)…”

Section: Acanthus Ilicifoliusmentioning

confidence: 99%

Searching for Natural Plants with Antimelanogenesis and Antityrosinase Properties for Cosmeceutical or Nutricosmetics Applications: A Systematic Review

Tung,

Yip,

Gew

2023

ACS Omega

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“…Esta análise da seletividade de substâncias apenas para células patogênicas é essencial na formulação dos fitoterápicos e fármacos em geral (Carneiro et al, 2016). Apesar disso, dos 13 estudos da amostra final, apenas 3 fizeram essa verificação, mostrando que mais trabalhos precisam ser feitos para conhecimento deste aspecto (Abu-Darwish et al, 2012;Carneiro et al, 2016;Sassi et al, 2020;York et al, 2012).…”

Section: Análise Dos Estudos Experimentais Selecionadosunclassified

Evaluación antimicrobiana de extractos etanólicos de aroeira (Schinnus terebinthifolius): Revisión

Silva¹,

Soares²,

Lima³

et al. 2022

Pubvet

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Diante do crescente surgimento de microrganismos resistentes, os tratamentos convencionais de algumas enfermidades que acometem os animais podem se tornar ineficazes, sendo necessária a formulação de novos medicamentos. Nesse sentido, tendo em vista que os fármacos geralmente são elaborados de compostos extraídos de plantas, esta é a razão de se pesquisar as atividades antimicrobianas das mais variadas espécies. Foi elaborada uma revisão de literatura com o objetivo de determinar se existe evidência científica disponível para apoiar a ação antimicrobiana da aroeira, especificamente de seus extratos etanólicos. A metodologia empregada para esta revisão reuniu os resultados dos estudos experimentais já elaborados, sem limite de ano de publicação. Para identificar trabalhos elegíveis foi realizada pesquisa nas bases de dados: PubMed, Portal Periódicos CAPES, ScienceDirect e Scopus e a documentação do processo de pesquisa bibliográfica foram utilizados os Itens de Relatórios para Revisões Sistemáticas e Meta-Análises (Preferred Reported Items for Systematic Review - PRISMA). Como critério de inclusão usou-se estudos que continham análise de extratos de plantas, idioma inglês, uso da Concentração Inibitória Mínima, avaliar atividade antimicrobiana ou antifúngica. A amostra final desta revisão resultou em um conjunto de 13 artigos, que continham os critérios de elegibilidade que melhor representaram as propriedades pesquisadas. Na análise destes estudos, verificou-se que o extrato etanólico da aroeira tem grande potencial para ser usado como antimicrobiano. Os resultados fornecem dados e perspectivas importantes sobre o uso da aroeira como antimicrobiano natural para o tratamento de doenças infecciosas. Para tal fim, o parâmetro utilizado foi a CIM (Concentração Inibitória Mínima) dos estudos selecionados, pois corresponde a um teste que permite avaliar a sensibilidade de patógenos a diversos produtos de origem natural e fitoterápicos.

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“…These medicinal properties are related to its high phenolic derivative content. Moreover, the methanol leaf extract of S. terebinthifolius has demonstrated the highest anti‐tyrosinase activity (% inhibition=100±0.0), followed by the acetone leaf extract (% inhibition=92.10±0.31), with hydroquinone as reference [12] …”

Section: Introductionmentioning

confidence: 98%

“…Moreover, the methanol leaf extract of S. terebinthifolius has demonstrated the highest anti-tyrosinase activity (% inhibition = 100 � 0.0), followed by the acetone leaf extract (% inhibition = 92.10 � 0.31), with hydroquinone as reference. [12] This study aims to investigate the interaction of the components of the leaf extract of S. terebinthifolius with human tyrosinase. The structure-based drug design (SBDD) was used to identify the component that is responsible for the inhibitory activity of the extract and to identify synthetic alterations that may improve its efficacy.…”

Section: Introductionmentioning

confidence: 99%

In SilicoInteractions of the Components from theSchinus terebinthifoliusExtract with Human Tyrosinase

et al. 2022

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The anti‐tyrosinase activity of the leaf extract of Schinus terebinthifolius, also known as Brazilian peppertree, was evaluated using multiple in silico approaches, such as molecular homology, molecular docking, MM‐GBSA, molecular dynamics, MM‐PBSA, QSAR, and skin permeability predictions. With these computational tools, the compounds that downregulate tyrosinase enzyme activity could be evaluated, and more potent molecules could be identified. The results indicated that various compounds, especially luteolin, are accountable for the anti‐tyrosinase activity of S. terebinthifolius. For cosmetic application, further studies with luteolin are especially recommended, for having presented a good performance both in theoretical inhibition (30.92 kJ mol−1) and skin permeability (LogKp=−6.62 cm−1).

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Phytochemical Profile and Antiproliferative, Anti-tyrosinase, Antioxidant, and Antibacterial Potential of Schinus terebinthifolius Growing in Tunisia

Cited by 4 publications

References 25 publications

Searching for Natural Plants with Antimelanogenesis and Antityrosinase Properties for Cosmeceutical or Nutricosmetics Applications: A Systematic Review

Searching for Natural Plants with Antimelanogenesis and Antityrosinase Properties for Cosmeceutical or Nutricosmetics Applications: A Systematic Review

Evaluación antimicrobiana de extractos etanólicos de aroeira (Schinnus terebinthifolius): Revisión

In SilicoInteractions of the Components from theSchinus terebinthifoliusExtract with Human Tyrosinase

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