Phytochemical profile and antioxidant activity of various solvent extracts of two varieties of ginger and garlic

Akullo, Jolly Oder; Kiage-Mokua, Beatrice N.; Nakimbugwe, Dorothy; Ng’ang’a, Jeremiah; Kinyuru, John

doi:10.1016/j.heliyon.2023.e18806

Cited by 8 publications

(3 citation statements)

References 62 publications

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“…IC50 is the concentration of antioxidant compounds that can reduce DPPH activity by 50%. A lower IC50 value indicates high antioxidant activity (Akullo et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Optimization of Antibacterial Metabolite Production and Antioxidant Activity of Endophytic Fungi Isolate from Kelakai (Stenochlaena palustris)

Muthma'innah Mashar,

Supriyono,

Suhaera

et al. 2023

FJST

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This research aims to optimize the production of antibacterial metabolites and test the antioxidant activity of endophytic isolates from kelakai (Stenochlaena palustris). The research results showed that the optimum growth profile of the isolate showed that exponential growth only started on day 1 and reached a maximum on day 17. Based on pH variations, it shows that pH 7 is the optimum pH in inhibiting bacterial growth, and based on variations in carbon sources, it shows that fructose is a better carbon source than glucose. Antimicrobial activity test using ethyl acetate extract from endophytic fungal fermentate based on differences in pH and carbon source showed antimicrobial activity against S. aureus and E. coli with the inhibition zone diameters being 13.50 mm and 11.35 mm, respectively.

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“…IC50 is the concentration of antioxidant compounds that can reduce DPPH activity by 50%. A lower IC50 value indicates high antioxidant activity (Akullo et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Optimization of Antibacterial Metabolite Production and Antioxidant Activity of Endophytic Fungi Isolate from Kelakai (Stenochlaena palustris)

Muthma'innah Mashar,

Supriyono,

Suhaera

et al. 2023

FJST

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“…Total flavonoids were reported as major constituents found in cardamom, clove, cinnamon, black pepper, cumin seed, fennel seed, red chili, coriander, and ginger [32]. Akullo et al [33] stated that garlic bulbs extracted with ethanol provided higher TPC than TFC, explaining the reason why spicy basil leaf curry contained higher TPC than Massaman curry, even when the spicy basil leaf curry was mainly garlic (45%) and dried basil leaves (35%). Chaudhary et al [34] reported that using methanol as the solvent for basil leaf extraction provided higher TFC than TPC.…”

Section: Total Phenolic and Flavonoid Contents And Antioxidant Activi...mentioning

confidence: 99%

Phytochemical Profiling and Antioxidant Activities of the Most Favored Ready-to-Use Thai Curries, Pad-Ka-Proa (Spicy Basil Leaves) and Massaman

Siripongvutikorn,

Pumethakul,

Yupanqui

et al. 2024

Foods

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Food is one of the factors with the highest impact on human health. Today, attention is paid not only to food properties such as energy provision and palatability but also to functional aspects including phytochemical, antioxidant properties, etc. Massaman and spicy basil leaf curries are famous Thai food dishes with a good harmony of flavor and taste, derived from multiple herbs and spices, including galangal rhizomes, chili pods, garlic bulbs, peppers, shallots, and coriander seeds, that provide an array of health benefits. The characterization of phytochemicals detected by LC-ESI-QTOF-MS/MS identified 99 components (Masaman) and 62 components (spicy basil leaf curry) such as quininic acid, hydroxycinnamic acid, luteolin, kaempferol, catechin, eugenol, betulinic acid, and gingerol. The cynaroside and luteolin-7-O-glucoside found in spicy basil leaf curry play a key role in antioxidant activities and were found at a significantly higher concentration than in Massaman curry. Phenolic and flavonoid compounds generally exhibit a bitter and astringent taste, but all the panelists scored both curries higher than 7 out of 9, confirming their acceptable flavor. Results suggest that the Massaman and spicy basil leaves contain various phytochemicals at different levels and may be further used as functional ingredients and nutraceutical products.

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“…New and alternative bioactive compounds can be discovered for the treatment of many diseases as a result of the isolation of plant‐derived secondary metabolites that have not yet been scientifically proven, but currently used in traditional medicine [4,5] . In recent years, many phytochemicals obtained from plants and having significant biological/pharmacological activity have been discovered [6–10] …”

Section: Introductionmentioning

confidence: 99%

Onosma demirizii: Chemical composition, antioxidant and enzyme inhibitory activity

Ozer,

Karan,

Ceylan

et al. 2024

ChemistrySelect

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The primary objectives of the present work were to determine the chemical composition, antioxidant potential and enzyme inhibitory activity of three extracts derived from Onosma demirizii (Boraginaceae), including methanol, water and ethyl acetate, and to chemically characterize the phytochemicals underlying this activity. A rapid, reproducible, simple, and sensitive method, which had been previously validated, was employed to identify 31 phenolics based on liquid chromatography electrospray ionization tandem mass spectrometry (LC‐ESI‐MS/MS). The conducted analysis of LC‐ESI‐MS/MS indicated that the methanol extract of O. demirizii was the richest in terms of both flavonoids and phenolics (42.75 mg GAEs/g extract and 59.90 mg QEs/g extract, respectively). The compounds with greatest abundance in methanol extract were hesperidin (177957 mg/g extract), chlorogenic acid (31815 mg/g extract), hyperoside (10199 mg/g extract), rosmarinic acid (8857 mg/g extract) and pinoresinol (2502 mg/g extract). Moreover, methanol extract exhibited the greatest activity in all antioxidant assays except for ferrous ion‐chelating assay. The EC50/IC50 values of the extract in CUPRAC and FRAP reducing power, phosphomolybdenum, DPPH and ABTS radical scavenging assays were determined to be 0.85, 1.47, 0.47, 1.78, and 1.67 mg/mL, respectively. However, the ferrous ion‐chelating assay was superior for water extract (1.07 mg/mL). Contrary to the results obtained from the assays of antioxidant activity, ethyl acetate extract was observed to be effective in enzymatic inhibition tests. The extract exhibited the highest activity against AChE and BChE (IC50 values 1.04 and 1.47 mg/mL, respectively). These extracts and compounds can be useful for the management of human diseases that are linked to oxidative stress.

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Phytochemical profile and antioxidant activity of various solvent extracts of two varieties of ginger and garlic

Cited by 8 publications

References 62 publications

Optimization of Antibacterial Metabolite Production and Antioxidant Activity of Endophytic Fungi Isolate from Kelakai (Stenochlaena palustris)

Optimization of Antibacterial Metabolite Production and Antioxidant Activity of Endophytic Fungi Isolate from Kelakai (Stenochlaena palustris)

Phytochemical Profiling and Antioxidant Activities of the Most Favored Ready-to-Use Thai Curries, Pad-Ka-Proa (Spicy Basil Leaves) and Massaman

Onosma demirizii: Chemical composition, antioxidant and enzyme inhibitory activity

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