Phytochemical, Pharmacological, and Biotechnological Study of Ageratina pichinchensis: A Native Species of Mexico

Abstract

Ageratina pichinchensis (Asteraceae) has been used for a long time in traditional Mexican medicine for treating different skin conditions and injuries. This review aimed to provide an up-to-date view regarding the traditional uses, chemical composition, and pharmacological properties (in vitro, in vivo, and clinical trials) that have been achieved using crude extracts, fractions, or pure compounds. Moreover, for a critical evaluation of the published literature, key databases (Pubmed, Science Direct, and SciFinder, among others) were systematically searched using keywords to retrieve relevant publications on this plant. Studies that reported on crude extracts, fractions, or isolated pure compounds of A. pichinchensis have found a varied range of biological effects, including antibacterial, curative, antiulcer, antifungal, and anti-inflammatory activities. Phytochemical analyses of different parts of A. pichinchensis revealed 47 compounds belonging to chromenes, furans, glycosylated flavonoids, terpenoids, and essential oils. Furthermore, biotechnological studies of A. pichinchensis such as callus and cell suspension cultures have provided information for future research perspectives to improve the production of valuable bioactive compounds.

Acknowledging the use of botanicals to treat diabetic foot ulcer during the 21st century: A systematic review

“…Ageratina pichinchensis ( A. pichinchensis ) is a wild plant native to Mexico[ 37 ]. In the Mexican state of Morelos, this plant is used in traditional medicine to prepare a remedy for skin lesions[ 38 ]. A chemical examination of this plant’s extract indicated the presence of chromones and compounds from the benzofurane group[ 39 , 40 ].…”

Efficacy of Acacia nilotica, Eucalyptus camaldulensis, and Salix safsafs on the mortality and development of two vector-borne mosquito species, Culex pipiens and Aedes aegypti, in the laboratory and field

“…The goal of these studies is to find out how to use many of these phytochemical compounds for different medical, therapeutic, and cosmetic purposes. These phytochemicals, derived or extracted from several aromatic plants such as Malva sylvestris, A. nilotica, Ageratina pichinchensis, E. camaldulensis, Capparis spinosa , and many other aromatic plants, are responsible for many pharmacological activities such as anti-inflammatory, antimicrobial, hepatoprotective, laxative, antiproliferative, and antioxidant [ [77] , [78] , [79] , [80] , [81] ].…”