Phytochemical identification of bangka origin virgin green coconut oil: Anti-inflammatory and anti-bacterial potential

Kardinasari, Emmy; Devriany, Ade

doi:10.1016/j.enfcli.2019.10.062

Cited by 9 publications

(11 citation statements)

References 13 publications

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“…Alkaloid content in VCO is high [24]. The antioxidant effect of alkaloid seemed to be higher than that of phenols [25] depend on its source.…”

Section: Discussionmentioning

confidence: 92%

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Antimalarial activity of Virgin Coconut Oil against Plasmodium berghei ANKA in mice

Widjanarko¹,

Wardhani²,

Arwati³

2022

International Journal of Scientific Advances

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Malaria remains a health problem in various parts of the world. A decrease in antioxidant levels during malaria infection cause oxidative stress, therefore exogenous antioxidant is needed. Virgin Coconut Oil (VCO) can be a source of exogenous antioxidants due to the antioxidant activity of VCO, which was contributed majority by phenolic acids content. Antioxidants play a role in countering the effects of free radicals by inhibiting fat peroxidation that cause erythrocyte cell wall stronger and not easily ruptured. Pharmacological properties of VCO including anti-inflammatory, anti-oxidant, antiviral, and antiprotozoal properties have been reported. Therefore, this study aimed to find out the antimalarial activity of VCO by evaluating the parasitemia and percentage of inhibition to the growth of parasite. Thirty male BALB/c mice were infected intraperitonially with 1×106 Plasmodium berghei ANKA-infected erythrocytes. The mice were than randomly divided into five groups: positive control (PC) group was given 187.2m g/kg BW of dihydroartemisinin phosphate, negative control (NC) group was only given sterile water; G1, G2, and G3 groups were given 1 ml, 5 ml, and 10 ml/kg BW of VCO, respectively. VCO treatments were given for 4 consecutive days started from 24 hours post infection. Parasitemia was determined daily on Giemsa-stained tail blood smear, further the percentage inhibition was calculated. The results showed that parasitemia in VCO-treated mice were lower than that of NC group, but higher than that of PC group, indicated the antimalarial activity of VCO. The inhibition of VCO to the growth of parasite showed that G2 was higher (48.70%) than that of G1 (13.04%) and G3 (33.9%). The use of antioxidant therapy as a supportive therapy is one of alternatives in supporting the healing process of malaria patients and may reduce various risks that could potentially occur in patients.

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“…Alkaloid content in VCO is high [24]. The antioxidant effect of alkaloid seemed to be higher than that of phenols [25] depend on its source.…”

Section: Discussionmentioning

confidence: 92%

“…The production of VCO can be different in the origin of raw materials [24] as well as their preparation that is resulting in different quality and quantity of contents [29], therefore the effect of different VCO found in the market may give different results.…”

Section: Discussionmentioning

confidence: 99%

Antimalarial activity of Virgin Coconut Oil against Plasmodium berghei ANKA in mice

Widjanarko¹,

Wardhani²,

Arwati³

2022

International Journal of Scientific Advances

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“…The addition of VCO was able to reduce the risk of the incidence rate, delayed onset, and mucositis toxicity by about 4 % [67]. Anti-inflammatory agents in VCO are bioactive compounds called polyphenols, and tocotrienols [14].…”

Section: Vco As An Anti-inflammatory Agentmentioning

confidence: 99%

“…VCO could also be transformed into biodiesel and bioethanol [9,10]. Nowadays, VCO is broadly utilized for biomedical applications as antibacterial and anti-microorganism [11][12][13][14][15][16], anti-inflammatory [4,14,17,18], super-absorbent [7], protection and remineralization agent for tooth [19,20], skin protector [21][22][23], immune booster [24], cancer inhibitor [25], blood pressure reducer [4], obesity reducer [26,27], treatment agent for neurodegenerative syndrome such as Alzheimer [28,29], and covid-19 treatment [30]. The utilization of VCO as a functional material in the -----health sector is generally carried out by direct supplementation or modifications into other forms, such as composite solutions, thin films, lotions, and emulsions [7,22,31,32].…”

Section: Introductionmentioning

confidence: 99%

Potential Loading of Virgin Coconut Oil into Centrifugally‐Spun Nanofibers for Biomedical Applications

2022

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Virgin coconut oil (VCO) has become a multifunctional material for biomedical applications due to its remarkable health benefits. The use of VCO for biomedical applications has seen tremendous growth over recent years, triggering researchers to develop various approaches for VCO utilization. Nanofibers‐based structure offers promising properties to encapsulate VCO, enhancing its performance and broadening its application in the medical field. Studies of VCO‐loaded polymeric nanofibers for biomedical applications are currently gradually rising. Recently, in nanofibers technology, centrifugal jet spinning (CJS) offers cost‐efficient and higher production rates to yield nanofibers compared to the other methods. This review summarizes recent advances of VCO for biomedical applications. Comprehensive suggestions for encapsulating VCO into nanofibers using the CJS technique are also provided. Highlights of future challenges in utilizing the CJS technique to produce VCO‐loaded nanofibers for biomedical applications are also elaborated.

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“…Minyak kelapa yang dihasilkan mempertahankan struktur fitokimia alami dan menghasilkan rasa dan aroma kelapa yang unik (Syah, 2005). Bidang mikrobiologi VCO dapat dimanfaatkan sebagai dapat dimanfaatkan sebagai anti bakteri (Kardinasari, 2020). Bakteri yang dapat dihambat perkembangannya yaitu Staphylococcus aureus.bakteri ini merupakan bakteri patogen yang dapat mengakibatkan berbagai penyakit pada manusia dan hewan (Widianingrum et al, 2019).…”

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Utilization Of Activated Charcoal From Nutmeg Shell Waste As An Adsorbent To Improve The Quality Of Virgin Coconut Oil (VCO) Fermentation Method

Hitijahubessy¹

2021

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Virgin coconut oil (VCO) is a form of processed coconut that is widely produced by people in Indonesia. VCO is often called pure coconut oil. VCO with good quality is by fermentation method using yeast. The quality of VCO can be measured by 3 types of analysis: water content, free fatty acids and peroxide number. The results of this analysis will be compared with the standards of the Asian and Pacific Coconut Community (APCC). VCO from fermentation method will be combined with the absorption method using nutmeg shell activated charcoal to see if there is a much better quality improvement. The results showed that there was a significant increase in quality with a decrease in the average water content from 0,1665% to 0,1005%. In addition, there was a significant decrease in the average free fatty acid content from 0,4681% to 0,3790% and significant decrease in average peroxide number from 0,1991 meq/kg to 0,0997 meq/kg. The results of the research on three VCO quality standards showed a value that was in accordance with the APCC standard.

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Phytochemical identification of bangka origin virgin green coconut oil: Anti-inflammatory and anti-bacterial potential

Cited by 9 publications

References 13 publications

Antimalarial activity of Virgin Coconut Oil against Plasmodium berghei ANKA in mice

Antimalarial activity of Virgin Coconut Oil against Plasmodium berghei ANKA in mice

Potential Loading of Virgin Coconut Oil into Centrifugally‐Spun Nanofibers for Biomedical Applications

Utilization Of Activated Charcoal From Nutmeg Shell Waste As An Adsorbent To Improve The Quality Of Virgin Coconut Oil (VCO) Fermentation Method

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