Phytochemical Evaluation and Radical Scavenging Activity of Bauhinia variegata, Saraca asoka and Terminalia arjuna Barks

Pandey, Ashok; Ojha, Vijayalakshmi; Yadav, Swati; Sahu, Sonu Kumar

doi:10.3923/rjphyto.2011.89.97

Cited by 24 publications

(18 citation statements)

References 14 publications

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“…The values obtained presently were much higher than earlier reports by Sadhu et al (2007), Pradhan et al (2010), Pandey et al (2011) and Ghatak et al (2015). Therefore, the Sa-O accession was chosen for the HPLC analysis of quercetin and catechin.…”

Section: Quantitative Analysiscontrasting

confidence: 63%

“…The results are in agreement with the reports of Sadhu et al (2007), Panchawat and Sisodia (2010), Pradhan et al (2010), and Manohar et al (2012) in S. asoca. Toxicity of some secondary metabolites of various plant parts was tested by while the antioxidant properties of bark and flower extracts were reported by Sadhu et al (2007), Panchawat and Sisodia (2010), Pandey et al (2011) and Pal et al (2014). Singh et al (2012) reported the antiacne property of the bark extract.…”

Section: Qualitative Analysismentioning

confidence: 99%

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Phytochemical studies of the endangered tree, Saracaasoca (Roxb.) De Wilde

Mohan¹,

Kumar²,

Naresh³

et al. 2017

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Saraca asoca (Roxb.) De Wilde. is an endangered medicinal tree that has immense medicinal importance. Six accessions of S. asoca were analyzed for phytochemicals to identify the accessions with the highest content of medicinal compou nds and to characterize two pharmaceutically important compounds. The chloroform and ethanol extracts of bark and the ethanol a nd chloroform extracts of flowers of the accessions were qualitatively tested for secondary metabolites. Total phenolics and flavonoids were also estimated to select the accessions with the highest content, which was further investigated by a sensitive and reliable high performance liquid chromatographic (HPLC) method for the pharmacologically important quercetin and catechin. The accession, Sa-O, identified based on the results of phytochemical analysis incidentally is the fifty-year-old ornamental tree on

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Section: Quantitative Analysiscontrasting

confidence: 63%

Section: Qualitative Analysismentioning

confidence: 99%

Phytochemical studies of the endangered tree, Saracaasoca (Roxb.) De Wilde

Mohan¹,

Kumar²,

Naresh³

et al. 2017

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“…A number of reports have described the presence of various antioxidant compounds such as ascorbic acid, catechin, flavonoids, lignin glycosides, -sitosterol and its glucosidic form, polyphenolics such as gallic acid in petroleum ether, chloroform and methanol extracts of S. asoca leaf, bark and flower 43,[46][47][48][49][50][51][52][53][54][55]67 . The flavonoid fraction of S. asoca flowers and leaves has been shown to inhibit -glucosidase and -amylase enzymes linked to type-2 diabetes and also prevent LDL (low density lipoprotein) oxidation 46,53,55 .…”

Section: Antioxidant Antidiabetic and Hypolipidemicmentioning

confidence: 99%

“…Lignin glycosides such as lyoniside, nudiposide, 5-methoxy-9--xylopyranosyl, isolariciresinol and schizandriside; flavonoids such as catechin, epicatechin, epiafzelechin-(48)-epicatechin, procyanidin B2, deoxyprocyanidin B, leukocyanidins and leucopelargonidin 61,81,82 ; and leucopelargonidin glucoside 83 have been reported from S. asoca bark 14,21,48,50,61,81,82 . Antioxidants such as polyphenolics, gallic acid and ellagic acid have also been described from S. asoca bark 14,21,38,43,[47][48][49]83 .…”

Section: Barkmentioning

confidence: 99%

Phytomedicinal Importance of <i>Saraca asoca</i> (Ashoka): An Exciting Past, an Emerging Present and a Promising Future

Singh¹,

Krishna²,

Kamalraj³

et al. 2015

Current Science

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Since the dawn of civilization, natural resources have remained the mainstay of various remedial approaches of humans vis-à-vis a large number of illnesses. Saraca asoca (Roxb.) de Wilde (Saraca indica L.) belonging to the family Caesalpiniaceae has been regarded as a universal panacea in old Indian Ayurvedic texts and has especially been used to manage gynaecological complications and infections besides treating haemmorhagic dysentery, uterine pain, bacterial infections, skin problems, tumours, worm infestations, cardiac and circulatory problems. Almost all parts of the plant are considered pharmacologically valuable. Extensive folkloric practices and ethnobotanical applications of this plant have even lead to the availability of several commercial S. asoca formulations recommended for different indications though adulteration of these remains a pressing concern. Though a wealth of knowledge on this plant is available in both the classical and modern literature, extensive research on its phytomedicinal worth using state-of-the-art tools and methodologies is lacking. Recent reports on bioprospecting of S. asoca endophytic fungi for industrial bioproducts and useful pharmacologically relevant metabolites provide a silver lining to uncover single molecular bio-effectors from its endophytes. Here, we describe socio-ethnobotanical usage, present the current pharmacological status and discuss potential bottlenecks in harnessing the proclaimed phytomedicinal worth of this prescribed Ayurvedic medicinal plant. Finally, we also look into the possible future of the drug discovery and pharmaceutical R&D efforts directed at exploring its pharma legacy.

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“…Ethyl-acetate fraction of the plant also produced considerable cytotoxicity against MCF-7 and THP-1cell lines [16,17,18,19,20,21,22]. Studies of ethanolic extracts of plant material showed the presence of carbohydrate, protein, glycosides, triterpenoids, saponins and steroids [23,24]. Extracts of B.variegata have antitumor, antimicrobial, antigoitrogenic, hepatoprotective and hemagglutination properties [25].…”

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confidence: 99%

Study of Phytochemical, Anti-Microbial, Anti-Oxidant, Phytotoxic, and Immunomodulatory Properties of Bauhinia variegata

Bhandari

Thapa²,

Niraula³

et al. 2017

JTLS

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In this paper, we investigated the anti-microbial, anti-oxidant, phytotoxic and immunomodulatory activity of plant Bauhinia variegata and also established the presence of important phytoconstituents which might signify its anticancer property. Phytochemical screening, anti-microbial assay, phytotoxicity assay, anti-oxidant assay and immunomodulatory analysis was done according to the protocol established at Department of Biotechnology, Kathmandu University and Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Pakistan. In the phytochemical screening, we observed the presence of different phytochemicals like steroids, terpenoids, flavonoids, reducing sugars and glycosides. In case of antimicrobial assay, the plant was found to be most effective against Bacillus cereus with the highest zone of inhibition (ZOI) of 12 mm and against Rhizopus with ZOI of 11 mm. During the antioxidant assay in comparison to ascorbic acid; at highest concentration, the scavenging activity shown by the plant B. variegata are 43.38% as compared to ascorbic acid 89.25%. In the immunomodulatory assay at the highest concentration i.e. 250 µg/mL, the plant showed 75.1% effect, which showed that the plant has potential anti-inflammatory potential. In phytotoxicity assay, B. variegata showed 20% phytotoxicity. B. variegata has thus been proven to be an important candidate to be used as an antimicrobial, antioxidant, anti-inflammatory, phytotoxic and anticancer agent. Separation of pure compounds with bioassay guided extraction, spectrometric analysis and subsequent cytotoxicity assay of the pure bioactive compounds from B. variegate is highly recommended as crude extract itself showed promising phytotoxicity and other pharmaceutical potential.

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Phytochemical Evaluation and Radical Scavenging Activity of Bauhinia variegata, Saraca asoka and Terminalia arjuna Barks

Cited by 24 publications

References 14 publications

Phytochemical studies of the endangered tree, Saracaasoca (Roxb.) De Wilde

Phytochemical studies of the endangered tree, Saracaasoca (Roxb.) De Wilde

Phytomedicinal Importance of <i>Saraca asoca</i> (Ashoka): An Exciting Past, an Emerging Present and a Promising Future

Study of Phytochemical, Anti-Microbial, Anti-Oxidant, Phytotoxic, and Immunomodulatory Properties of Bauhinia variegata

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