Phytochemical constituents of sterol‐rich fraction from Allium cepa L. and its cytotoxic effect on human embryonic kidney (HEK293) cells

Abstract

Allium Cepa, commonly known as onions, is among the common vegetables consumed globally. It is the most common specie of the genus, Allium belonging to the Amaryllidaceae family. A. cepa is present in various varieties, with the most common being the red, yellow, and white varieties (Albishi et al., 2013). It is an important ingredient for most cuisines cutting across Africa, Asia, and the America. It adds flavor to food as well as contributes to the nutritional properties as it is a source of major micronutrients particularly the vitamins and minerals (Ali & Tsou, 1997). A. cepa has also been reported for its medicinal properties owing to its phytochemical components, with quercetin being the key flavonoid (Albishi et al., 2013; Kwak et al., 2017), and pyruvic acid, its major sulfur compounds (Gîtin et al., 2014). A. cepa has been well documented for its potent antioxidant activities as evident by its free radicals scavenging and redox imbalance ameliorative abilities in several diseases

Synthesis of Eco-Friendly Silver Nanoparticles Using Glycyrrhizin and Evaluation of Their Antibacterial Ability

“…We studied the cytotoxic properties of glycyrrhizin-reduced AgNPs and sodium citrate-reduced AgNPs at different concentrations. Human embryonic kidney 293A (HEK293) cells obtained from Invitrogen were used in this experiment [ 15 ]. An MTT colorimetric assay was used to evaluate the cytotoxic effect of AgNPs on HEK293 cells with a 96-well plate [ 16 ].…”