Phytochemical compositions, antimicrobial activities, and thin layer chromatography analysis of aqueous, and methanol extracts of Tectona grandis leaf

Muhammed, Hadiza Lami; Abdullahi, Lare H.; Mayaki, Fatima G.; Boko, Usman H.

doi:10.53858/arocnpr01014451

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…Segun EN Steroid, tannin, saponin, coumarin, protein, carbohydrate, phytosterol, alkaloid, diterpenes and Phlobatannins. [55] Lamiaceae Vitex negundo L.; Digha 13…”

Section: Iucn Statusmentioning

confidence: 99%

Status of Tree Diversity in Digha, West Bengal, India with Special Reference to their Phytochemical Constituents

Bera,

Samanta,

Panda

2024

Pharmacogn Res.

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Background: Digha is a coastal area in the district of Purba Medinipur, West Bengal, India. The vegetation in this area is unstable, like many other coastal zones. Trees play an important role in this region to prevent soil erosion and act as a windbreak. Also, the local people here depend on trees for their livelihood. Objectives: The current study aims to enumerate the tree species growing along the Digha seashore with special reference to their IUCN status and phytochemical constituents. Materials and Methods: The study area was rigorously surveyed over a period of about 4 years to record the trees of the area. Standard literature and websites were followed to summarize IUCN status and chemical constituents of the documented trees. Results: A total of 65 tree species belonging to 59 genera, and under 28 families have been documented with Fabaceae contributing the most (14 species). Tectona grandis was the only endangered tree species among the plants recorded. Conclusion: Conservation strategies must be adopted by the Forest Department and other government organizations to protect the relevant tree species as well as this fragile biozone.

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“…Segun EN Steroid, tannin, saponin, coumarin, protein, carbohydrate, phytosterol, alkaloid, diterpenes and Phlobatannins. [55] Lamiaceae Vitex negundo L.; Digha 13…”

Section: Iucn Statusmentioning

confidence: 99%

Status of Tree Diversity in Digha, West Bengal, India with Special Reference to their Phytochemical Constituents

Bera,

Samanta,

Panda

2024

Pharmacogn Res.

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“…The antimicrobial activities of these plants are due to the presence of secondary metabolites present mainly in the leaves, as they are the site for the synthesis of bioactive compounds, hence the presence of high concentrations of active compounds and antibacterial activities in the leaves (Moses et al, 2019). These bioactive compounds, phytochemicals, are known for their interference with the proteins and enzymes of the microbial cell membrane, destroying its structure, leading to the inhibition of various cell functions and the eventual death of the microorganism (Mostafa et al, 2018;Muhammed et al, 2021).…”

Section: Minimum Bactericidal Concentration (Mbc)mentioning

confidence: 99%

Antibacterial Properties and Phytochemicals Screening of Tectona grandis (Teak) Leaf Extracts against Bacteria Implicated from Upper Respiratory Tract Infections

Usin¹

2022

JMR

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Upper respiratory tract infections (URTIs) commonly befalls both children and adults and is a major cause of mild morbidity. URTIs ranges from mild self-limiting diseases such as common cold to serious life-threatening illnesses such as epiglottitis. The present study was aimed to evaluate the antibacterial activities of Tectona grandis (teak) leaves extractson some pathogenic microorganisms isolated from clinical samples causingURTIs. The antibacterial activities were assayed using the agar well diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated using standard microbiological techniques. Phytochemical andmineral compositions of all the extracts were determined. Appreciable quantities of phytochemical such as saponins, tannins, flavonoids, glycosides, anthraquinone and alkaloids were present in both extracts of the plants with flavonoids having a higher percentage. Minerals such as K, Ca, Fe, Na and Fe were presented in both solvents. Heavy metals like Pb, Cd and as were presented in significant quantities in both extracts, however, high amount of the heavy metal composition was observed in the ethanol extract. The plant extracts exhibited varying degrees of concentration-based antibacterial activities against bacteria implicated from URTIs. They showed a high significant antibacterial activity against Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. Conclusively, the plant extracts contained several bioactive compounds (phytochemical), thereby validating the use of this plants for therapeutic tenacities. Also, the antibacterial activity of the leaf extracts against the test organisms also supports its usage in traditional medicine practice.

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Anthelmintic Activity of Alcoholic Leaf Extract of Tectona grandis

Nair,

S.,

Rajaselvi

et al. 2024

Journal of Pharmacology and Pharmacotherapeutics

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Background: Helminthiasis is a major concern in the livestock sector due to the immense afflictions in the production and economy of the farmer. Chemical anthelmintics are used to combat them and parasites are acquiring resistance against these drugs. Hence, the development of new drugs or alternatives is the need of the hour for combating such infestations. This study was undertaken to determine the effect of methanolic leaf extract of Tectona grandis on strongyles. Materials and Methods: The dried leaves of Tectona grandis were subjected to Soxhlet extraction using methanol, and the extract was tested for its anthelmintic activity in vitro using egg hatch assay and larval motility assay. A dose of 250, 125, 62.5, 31.25, 15.625, and 7.8125 mg/ mL was used for the study. Fresh strongyle ova were exposed to different concentrations of the extract and observed after 48 hours for the hatch. L3 larvae obtained from coproculture were subjected to treatment with extract at different concentrations, and mortality per unit time was calculated. Fourier transform infrared (FTIR) spectroscopic analysis and Gas chromatography-mass spectrometry (GC/MS) were performed to identify the chemical nature of the extract. Results: There was a dose-dependent inhibition of hatch and larval mortality with a maximum inhibition of hatch at 250 mg/mL. There was a cent percent hatch in control wells and no loss of progressive motility in the larval motility test. On exposure to the extract, the larvae progressively lost their motility, and finally, there were caesurae of movement which indicated their death. The extract at 250 mg/mL killed all the larvae by 30 min, whereas, at 31.25 mg/mL, the mortality was 66.6% after 2 hr. Conclusion: The results suggest that methanolic extract from Tectona grandis leaves has a promising anthelmintic property and further studies are required for the isolation of active molecules.

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Phytochemical compositions, antimicrobial activities, and thin layer chromatography analysis of aqueous, and methanol extracts of Tectona grandis leaf

Cited by 3 publications

References 6 publications

Status of Tree Diversity in Digha, West Bengal, India with Special Reference to their Phytochemical Constituents

Status of Tree Diversity in Digha, West Bengal, India with Special Reference to their Phytochemical Constituents

Antibacterial Properties and Phytochemicals Screening of Tectona grandis (Teak) Leaf Extracts against Bacteria Implicated from Upper Respiratory Tract Infections

Anthelmintic Activity of Alcoholic Leaf Extract of Tectona grandis

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