Phytochemical characterization and evaluation of anticataract potential of seabuckthorn leaf extract

Dubey, Sudhisha; Deep, Prakash; Singh, Amrit

doi:10.1111/vop.12271

Cited by 20 publications

(13 citation statements)

References 28 publications

(28 reference statements)

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“…LI 56Steroids, alkaloids, phenolics, flavonoids, tannins and terpenoids [185]Nephrotoxicity [186]37.Cupressaceae Juniperus excelsa M. Bieb. LI 57Alkaloids,flavonoids, phenols, saponins and diterpenes [187]Cytotoxicity [188]38.Cyperaceae Cyperus difformis L LI 38Flavonoids, coumarins, tannins and sterols [189]Fumigent toxicité [190](Chang et al, 2012)39.Elaeagnacea e Hippophae rhamnoides L. LI 53Phenol, Quercetin and Catechin [191]Non toxic [192]40.Equisetaceae Equisetum arvense L. LI 43Flavonoids, alkaloids, minerals, phenolic petrosins, triterpenoids, saponins, phytosterols [193]Acute and metal toxicity [194]41.Euphorbiaceae Euphorbia helioscopia L. LI 44Reducing sugars, terpenoids, alkaloids, steroids, tannins, flavanoids and phenolic compounds [195]Cytotoxicity [196]42.Fabaceae Butea monosperma (Lam.) Kuntze LI 14Sterols, triterpenes, glycosides flavonoids and proteins [197].…”

Section: Resultsmentioning

confidence: 99%

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan

Malik

Ahmad

Zafar

et al. 2019

BMC Complement Altern Med

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Background Skin diseases are a major health concern especially in association with human immune deficiency syndrome and acquired an immune deficiency. The aim of this study was to document the ethnomedicinal information of plants used to treat skin diseases in Northern Pakistan. This is the first quantitative ethnobotanical study of therapeutic herbs utilized by the indigenous people of Northern Pakistan for skin diseases. Methods Interviews were taken to obtain information from 180 participants. Quantitative methods including fidelity level (FL), Frequency of citation (FC), Use-value (UV), Jaccard indices (JI), Family importance value (FIV), Relative frequency of citation (RFC) and Chi-square test were applied. Medicinal plants uses are also compared with 50 national and international publications. Results In this study, we recorded 106 plant species belonged to 56 floral families for treatment of skin ailments. The dominant life form reported was herb while the preferred method of utilization was powder, along with leaf as the most used plant part. RFC ranges from 0.07 to 0.25% whereas the highest FIV was recorded for family Pteridaceae. FL values range from 36.8 to 100%. The study reported 88% of new plant reports for the treatment of skin diseases. Conclusion The present study revealed the importance of several plants used to treat skin diseases by the local communities of Northern Pakistan. The available literature supported the evidence of plant dermatological properties. Plants having high UV and RFC can be considered for further scientific analysis. There is dire need to create awareness among local, government and scientific communities for the preservation of medicinal species and ethnomedicinal knowledge in Northern Pakistan. Electronic supplementary material The online version of this article (10.1186/s12906-019-2605-6) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan

Malik

Ahmad

Zafar

et al. 2019

BMC Complement Altern Med

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“…Leaf extracts of seabucthorn have been shown to possess potent antioxidant activity in C-6 glioma cells, in vitro [143]. The aqueous extract of seabuckthorn leaf delayed initiation and progression of H 2 O 2 -induced cataract formation and restored GSH, SOD activity in goat lenses, ex vivo [144].…”

Section: Plant-derived Compounds and Herbal Extractsmentioning

confidence: 99%

Current Trends in the Pharmacotherapy of Cataracts

et al. 2020

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Cataracts, one of the leading causes of preventable blindness worldwide, refers to lens degradation that is characterized by clouding, with consequent blurry vision. As life expectancies improve, the number of people affected with cataracts is predicted to increase worldwide, especially in low-income nations with limited access to surgery. Although cataract surgery is considered safe, it is associated with some complications such as retinal detachment, warranting a search for cheap, pharmacological alternatives to the management of this ocular disease. The lens is richly endowed with a complex system of non-enzymatic and enzymatic antioxidants which scavenge reactive oxygen species to preserve lens proteins. Depletion and/or failure in this primary antioxidant defense system contributes to the damage observed in lenticular molecules and their repair mechanisms, ultimately causing cataracts. Several attempts have been made to counteract experimentally induced cataract using in vitro, ex vivo, and in vivo techniques. The majority of the anti-cataract compounds tested, including plant extracts and naturally-occurring compounds, lies in their antioxidant and/or free radical scavenging and/or anti-inflammatory propensity. In addition to providing an overview of the pathophysiology of cataracts, this review focuses on the role of various categories of natural and synthetic compounds on experimentally-induced cataracts.

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“…The process of cataractogenesis was delayed. It delayed the onset and subsequent maturation of cataract [70,71].…”

Section: Anticataract Activitymentioning

confidence: 99%

Pharmacological Evaluation of Ocimum sanctum

Bano¹,

Ahmed²,

Tanveer³

et al. 2017

J Bioequiv Availab

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Phytochemical characterization and evaluation of anticataract potential of seabuckthorn leaf extract

Abstract: Aqueous extract of SBT leaves showed the potential to delay onset and/or progression of cataract, at least during in vitro conditions. Results indicate the possibilities of evaluating this extract for its use as anticataract agent during in vivo conditions.

Cited by 20 publications

References 28 publications

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan

Current Trends in the Pharmacotherapy of Cataracts

Pharmacological Evaluation of Ocimum sanctum

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