Phytochemical Characterization and Bioactivity of Asparagus acutifolius: A Focus on Antioxidant, Cytotoxic, Lipase Inhibitory and Antimicrobial Activities

Hamdi, Amel; Jaramillo, Sara; Rodríguez-Arcos, Rocío; Jiménez-Araujo, Ana; Lachâal, Mokhtar; Karray‐Bouraoui, Najoua; Guillén, Rafael

doi:10.3390/molecules26113328

Cited by 16 publications

(18 citation statements)

References 43 publications

(85 reference statements)

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“…Studies have found that it can reduce the risk of cardiovascular and cerebrovascular diseases such as cancer and high blood pressure [ 26 , 27 , 28 , 29 , 30 ]. Asparagus is a vegetable in daily diet and has potential to develop functional products [ 31 ]. Therefore, understanding the metal contents, pollution levels, and health risks in asparagus and soil is of great significance to ensure the ecological safety of soil, the planting and consumption safety of asparagus, and ultimately the economic benefits of asparagus in Chongming area.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Contents and Health Impacts of Four Metals in Chongming Asparagus—Geographical and Seasonal Aspects

Zhang

Jia

et al. 2022

Foods

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In this paper, the contents of four typical metals (Pb, Cd, Hg, and As) in asparagus, water, and soil from Chongming Island were quantitatively determined by inductively coupled plasma mass spectrometry (ICP-MS). The contents of these metals in asparagus showed a common rule of Pb > As > Cd > Hg in different harvest seasons and regions. Significant seasonal differences were found in the contents by difference analysis, but no obvious regional differences were observed. Furthermore, the asparagus did not accumulate these four metals from the soil in Chongming Island by the assessment of bio-concentration factor. The asparagus was proved safe by the analysis of single-factor pollution index and Nemerow pollution index. Through combining the analysis of the above indexes and the geological accumulation index, we found that 51.62% of soil samples were mildly polluted by cadmium. The results of health risk analysis showed that the risk value of children was higher than that of adults under oral exposure, but the four metals in asparagus possessed no obvious risk to health. The above assessments illustrate that the daily consumption of asparagus in Chongming Island will not cause potential health impacts. It is of benefit to ensure the quality and economic interests of asparagus planting in Chongming Island through the investigation of this study.

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Section: Introductionmentioning

confidence: 99%

Assessment of Contents and Health Impacts of Four Metals in Chongming Asparagus—Geographical and Seasonal Aspects

Zhang

Jia

et al. 2022

Foods

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“…Several reports indicated that saponins especially those with steroidal nucleus, flavonoid, and phenols are among the major constituents isolated from the genus Asparagus. Several other minor classes such as alkaloids, tannins, minerals, and amino acids were also reported from Asparagus species [50][51][52] .…”

Section: Resultsmentioning

confidence: 99%

Phytochemical and Pharmacological Values of Two Major Constituents of Asparagus Species and their Nano formulations: A Review

Sobhy

Mady

Mina

et al. 2022

Journal of Advanced Pharmacy Research

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Objectives: This review article highlights two of the major chemical classes and their derivatives frequently isolated from different species of genus Asparagus and the diversity of their biological activities in addition to different applications of genus Asparagus in nanoformulation. The species belonging to this genus are well known for their nutritional and medicinal benefits and are considered one of the promising sources of biologically active natural compounds. Among the major constituent detected in the genus Asparagus are saponins and flavonoids to which most of the biological activities are attributed. Methods: This review includes a collection of articles between 2000 to 2022, reviewed by internationally accepted databases and scientific journals. Results: This review demonstrates the structural and biological diversities of fifty-three saponin aglycones and glycosides and nineteen flavonoids and flavonoid glycosides isolated from different Asparagus species highlighting their structural diversity along with the biological activities of the reviewed species highlighting their structural diversity along with the biological activities of the reviewed species. Moreover, the application of Asparagus extracts for green synthesis of metal-based nanoparticles to minimize the hazardous effect on the environment and humans observed with metal-based nanoparticles chemically synthesized. Conclusion: The structural and biological diversities and potency of the reviewed saponins and flavonoids isolated from Asparagus along with their use in the production of stable nanoformulations made them a perfect candidate for future drug discovery of new pharmaceutically active agents.

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“…Conversely, the aqueous extract was more effective against A. niger and C. albicans. Hamdi et al 25 studied the phytochemical composition and antimicrobial activity of different parts of Asparagus acutifolius and came to the conclusion that the extract from the leaves of the plant was more effective.…”

Section: Edible Plantsmentioning

confidence: 99%

Antimicrobial activity of saponin-containing plants: review

Alina,

Kiełb Ewa,

František

2023

JDVAR

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The resistance of pathogenic microorganisms to antibiotics has become a "scourge" of the medical field in recent decades. In this regard, the vector of medical research rightly changed in favor of the search for natural mechanisms to fight pathogens. Nature has produced mechanisms for maintaining balance for millions of years, so it is reasonable to investigate and, in the future, use such mechanisms. This current study reviews and analyzes the last five years of research on the effects of saponin-containing plants on the most common pathogens. The analysis of literary data confirms the growing interest in natural antimicrobial drugs that are currently used in folk medicine or have the prospect of use in humane medicine in different countries of the world. Wide interest of the scientific community in the search for alternative antimicrobial agents, which would make it possible to overcome antibiotic resistance in the treatment of various types of diseases, has been revealed. Current scientific research has confirmed or disproved the effectiveness of only a thousandth part of all possible plants. Undoubtedly, the use of natural plant components will make it possible to make the treatment process cheaper and more effective, so this direction of research is currently very promising from all points of view.

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Phytochemical Characterization and Bioactivity of Asparagus acutifolius: A Focus on Antioxidant, Cytotoxic, Lipase Inhibitory and Antimicrobial Activities

Cited by 16 publications

References 43 publications

Assessment of Contents and Health Impacts of Four Metals in Chongming Asparagus—Geographical and Seasonal Aspects

Assessment of Contents and Health Impacts of Four Metals in Chongming Asparagus—Geographical and Seasonal Aspects

Phytochemical and Pharmacological Values of Two Major Constituents of Asparagus Species and their Nano formulations: A Review

Antimicrobial activity of saponin-containing plants: review

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