Phytochemical and pharmacological review on Stephania japonica

Abstract

ARTICLE INFOThis paper reviews phytochemical and pharmacological profiles of Stephania japonica from the databases PubMed, Science Direct and Google Scholar up to December 2018. S. japonica is a common plant, widely distributed in all over Bangladesh. Traditionally, this plant is considered as one of the important medicinal plants in the treatment of a variety of ailments, including inflammation, pain, rheumatism, cancer, bone fracture and fever. Findings suggest that S. japonica is rich in important phytochemicals, including alkaloids, steroids, saponins and fats. It is evident to possess anti-inflammatory, antioxidant, antidiarrheal, antimicrobial, insecticidal, anti-nociceptive, neuro-protective, analgesic and anti-hyperglycaemic activities. In conclusion, S. japonica may be one of the best sources of plant-based active constituents.

Mortality and larvicidal activity of aqueous extract of Stephania japonica leaf against the larva of the mosquito Anopheles culicifacies

“…The death of mosquito larvae is caused by the bioactive compounds in S. japonica leaf extract, which act as toxicants. The bioactive compounds contained in Stephania genus leaf extract include alkaloids and terpenoids [20][21] . Toxic compounds that enter the insect's body can cause a decrease in the insect's growth rate.…”