PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW OF LICORICE (Glycyrrhiza sp.) - A TRADITIONAL LOCAL HERB FOR THE FUTURE OF MEDICINE

Abstract

The genus Glycyrrhiza (Fabaceae), with over 30 species, includes plants with abundant medicinal properties that have been prevalently used for a long time in traditional medicine. Today, along with the rapid development of modern medicine, this traditional medicine still plays an important role in the research and development of many new drugs. This report emphasized the contribution of some major components of Cam thao (Licorice), one of the species with multifaceted pharmacological effects and used to produce new drugs. Numerous studies have discovered that Licorice contains important substances that affect the physiological activities of living organisms, such as liquirtin, rhamnoliquirilin, liquiritigenin, prenyllicoflavone A, glucoliquiritin apioside, 1metho-xyphaseolin, shinpterocarpine, shinflavanone, licopyranocoumarin, isoflavone, licoarylcoumarin, glycyrrhizin, and manifold components. In this review, the most recent research results within the last 5 years on the pharmacological effects of Licorice are systemized according to the role of Licorice on nervous, respiratory, digestive, immune, reproductive systems (both male and female) and metabolism. It is predicted that Licorice (Fabaceae) will certainly continue to be the subject of manifold scientific works in the future. The effects that have been interesting in the scientific community recently are: oxidation prevention, memory impairment prevention, weight loss, reproductive function improvement in obese men, and immune system function enhancement in many types of cancer. In addition, previous and ongoing studies have shown that Glycyrrhizin, an active ingredient found in Licorice, is effective against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) because of its antiviral activity. As a result, Licorice can be considered a promising future herbal medicine vital to individual and community health.

Recent Advances in the Management of Rosacea through Natural Compounds

“…Licorice has long been used in alternative medicine to treat various inflamm conditions due to its complex botanical composition. G. glabra is known to be espe rich in flavonoids and saponins (glabridin, glychyrrizic acid, glycyrrhizin, lichocha and liquiritigenin), but also polysaccharides and other phenols [61]. Some of the studied compounds in G. glabra are glabridin and glycyrrhizin, both of which are in higher quantities and have anti-irritant and anti-inflammatory properties [62,63 cause it inhibits the generation of superoxide anion and cyclooxygenase activity, li has been demonstrated to have anti-inflammatory properties [64].…”