Phytochemical and Biological Properties of Sesquiterpene Constituents From the Marine Red Seaweed Laurencia: A Review

Al-Massarani, Shaza M.

doi:10.4172/2329-6836.1000147

Cited by 6 publications

(3 citation statements)

References 110 publications

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“…The spectrum of seaweed extracts clearly showed the absence of Ag and CuO peaks in the extract. Thus, the main responsible components for the reduction, capping and stability of AgNPs, CuONPs, and Ag–CuO NCS were sesquiterpenes, phenolics, acids, proteins, and polysaccharides present in the extract of L. dendroidea seaweed ( Al-Massarani, 2014 ).…”

Section: Resultsmentioning

confidence: 99%

Advanced polymeric metal/metal oxide bionanocomposite using seaweedLaurencia dendroideaextract for antiprotozoal, anticancer, and photocatalytic applications

Amina

Musayeib

Alterary

et al. 2023

PeerJ

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Background Biosynthesized nanoparticles are gaining popularity due to their distinctive biological applications as well as bioactive secondary metabolites from natural products that contribute in green synthesis. Methodology This study reports a facile, ecofriendly, reliable, and cost-effective synthesis of silver nanoparticles (AgNPs), copper oxide nanoparticles (CuONPs), and polymeric PVP-silver-copper oxide nanocomposite using ethanol extract of seaweed Laurencia dendroidea and were evaluated for antiprotozoal, anticancer and photocatalytic potential. The nanostructures of the AgNPs, CuONPs, and polymeric PVP-Ag-CuO nanocomposite were confirmed by different spectroscopic and microscopic procedures. Results The UV-vis spectrum displayed distinct absorption peaks at 440, 350, and 470 nm for AgNPs, CuONPs, and polymeric Ag-CuO nanocomposite, respectively. The average particles size of the formed AgNPs, CuONPs, and Ag-CuO nanocomposite was 25, 28, and 30 nm, respectively with zeta potential values −31.7 ± 0.6 mV, −17.6 ± 4.2 mV, and −22.9 ± 4.45 mV. The microscopic investigation of biosynthesized nanomaterials revealed a spherical morphological shape with average crystallite sizes of 17.56 nm (AgNPs), 18.21 nm (CuONPs), and 25.46 nm (PVP-Ag-CuO nanocomposite). The antiprotozoal potential of green synthesized nanomaterials was examined against Leishmania amazonensis and Trypanosoma cruzi parasites. The polymeric PVP-Ag-CuO nanocomposite exerted the highest antiprotozoal effect with IC50 values of 17.32 ± 1.5 and 17.48 ± 4.2 µM, in contrast to AgNPs and CuONPs. The anticancer potential of AgNPs, CuONPs, and polymeric PVP-Ag-CuO nanocomposite against HepG2 cancer cell lines revealed that all the nanomaterials were effective and the highest anticancer potential was displayed by PVP-Ag-CuO nanocomposite with IC50 values 91.34 µg mL−1 at 200 µg mL−1 concentration. Additionally, PVP-Ag-CuO nanocomposite showed strong photocatalytic effect. Conclusion Overall, this study suggested that the biogenic synthesized nanomaterials AgNPs, CuONPs, and polymeric PVP-Ag-CuO nanocomposite using ethanol extract of seaweed L. dendroidea possesses promising antiprotozoal anticancer and photocatalytic effect and could be further exploited for the development of antiprotozoal and anticancer therapeutics agents.

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Section: Resultsmentioning

confidence: 99%

Advanced polymeric metal/metal oxide bionanocomposite using seaweedLaurencia dendroideaextract for antiprotozoal, anticancer, and photocatalytic applications

Amina

Musayeib

Alterary

et al. 2023

PeerJ

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“…Given the limited variety of red macroalgae explored for this purpose, according to the research, the genus Laurencia was the most often used in crude extracts. Laurencia species have been studied for years, revealing this to be a very rich genus in bioactive metabolites, such as diterpenes, triterpenes, sesquiterpenes, steroids, aromatic compounds, and indoles, among others [95], and sesquiterpenoids are the main constituents from this genus [96]; among other properties, they are known to possess potent antibacterial activities against methicillin-resistant S. aureus (MRSA), penicillin-resistant Streptococcus pneumoniae, and vancomycin-resistant Enterococcus faecalis [97]. From a crude methanol extract of R. confervoides, ten bromophenols were isolated, confirming the reputation of the richness in bromophenol metabolites of the genus Rhodomela [93,94].…”

Section: Antibacterials From Red Macroalgaementioning

confidence: 99%

Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care

Januário

Félix

et al. 2021

Pharmaceutics

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Acne vulgaris (AV) is a chronic skin disease of the pilosebaceous unit affecting both adolescents and adults. Its pathophysiology includes processes of inflammation, increased keratinization, sebum production, hormonal dysregulation, and bacterial Cutibacterium acnes proliferation. Common AV has been treated with antibiotics since the 1960s, but strain resistance has emerged and is of paramount concern. Macroalgae are known producers of substances with bioactive properties, including anti-viral, antibacterial, antioxidant, and anti-inflammatory properties, among several others. In particular, red algae are rich in bioactive compounds such as polysaccharides, phenolic compounds, lipids, sterols, alkaloids, and terpenoids, conferring them antioxidant, antimicrobial, and anti-inflammatory activities, among others. Thus, the exploration of compounds from marine resources can be an appealing approach to discover new treatment options against AV. The aim of this work is to provide an overview of the current knowledge of the potentialities of red macroalgae in the treatment of AV by reviewing the main therapeutic targets of this disease, and then the existence of compounds or extracts with bioactive properties against them.

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“…An important halosesquiterpene characteristic of the family Rhodomelaceae is elatol (103); it is isolated from L. elata [128] and from several other species of Laurencia [129]. An exhaustive literature review has described the chemical structure data and biological activities of the halogenated sesquiterpenes of red algae [130,131].…”

Section: Halogenated Terpenes From Red Algae (Rhodophyta)mentioning

confidence: 99%

Algae Essential Oils: Chemistry, Ecology, and Biological Activities

Hattab¹

2020

Essential Oils - Bioactive Compounds, New Perspectives and Applications

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This chapter focuses on the essential oils and volatile fractions of seaweed. It includes an introduction to the essentials and volatile fractions and the main chemical classes found. This part is completed by a presentation of the fundamental aspects of biodiversity and the chemodiversity of the marine environment followed by the taxonomy and systematics of marine macroalgae. The heart of this chapter concerns the chemistry of volatile products extracted from marine algae. It reports the specificities of the marine natural products chemistry in comparison to that of terrestrial organisms. The description of volatile compounds in seaweed is divided into two parts, the first reports the common compounds identified in main volatile fractions and the second cover the specific volatile components. These include C11 hydrocarbons, sulfur compounds, and halogenated hydrocarbons. These latter are playing a very important role in communication and chemical defense. The last part includes aspects of chemical ecology and biological activities of volatile products.

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Phytochemical and Biological Properties of Sesquiterpene Constituents From the Marine Red Seaweed Laurencia: A Review

Cited by 6 publications

References 110 publications

Advanced polymeric metal/metal oxide bionanocomposite using seaweedLaurencia dendroideaextract for antiprotozoal, anticancer, and photocatalytic applications

Advanced polymeric metal/metal oxide bionanocomposite using seaweedLaurencia dendroideaextract for antiprotozoal, anticancer, and photocatalytic applications

Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care

Algae Essential Oils: Chemistry, Ecology, and Biological Activities

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