Phytochemical and antimicrobial studies of Begonia malabarica

Nachimuthu, Ramesh; Viswanathan, M. B.; Saraswathy, A; Balakrishna, K.; Brindha, P.; Lakshmanaperumalsamy, P.

doi:10.1016/s0378-8741(01)00352-x

Cited by 42 publications

(32 citation statements)

References 5 publications

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“…Prescott et al (1999) and Stanier et al (1986) reported diseases such as pneumonia, urinary and respiratory tract infection, noscomial pathogens and opportunistic infections caused by Klebsiella species. Ramesh et al (2001a) implicated the ethnotherapeutic use in respiratory tract diseases by Paliyans based on the antibacterial activity exhibited by chloroform and methanol extracts of Begonia malabarica against Klebsiella pneumoniae. Ramesh et al (2001b) provided scientific evidence for another ethnotherapeutic use of the Paliyans in urinary tract infections based on the activity of the bark methanol extract of Bridelia crenulata against Klebsiella pneumoniae.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial potential from Indian Suregada angustifolia

Venkatesan

Viswanathan

Nachimuthu³

et al. 2005

Journal of Ethnopharmacology

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Section: Discussionmentioning

confidence: 99%

Antibacterial potential from Indian Suregada angustifolia

Venkatesan

Viswanathan

Nachimuthu³

et al. 2005

Journal of Ethnopharmacology

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“…The activity of the same extracts against Vibrio parahaemolyticus suggests the use of the plant in diarrhea. The activity of the chloroform and aqueous extracts against Chromobacterium violaceum supports the use of plant against skin lesions and pyemia (Ramesh et al, 2002).…”

Section: Resultsmentioning

confidence: 61%

“…In another study, aqueous leaves extract showed antimicrobial activity against the Gram-negative bacteria except for Vibrio parahaemolyticus. Nevertheless, the chloroform and methanol extracts showed minimum activity against all the tested bacteria (Ramesh et al, 2002 Jeeva et al (2012). In addition, the results of the phytochemical screening, conducted by these authors, revealed that extract of Begonia floccifera flowers screened contained phenol, tannins, xanthoproteins, steroids, tannins, steroids, phytosterols, triterpenoids, sapogenins, coumarins and carbohydrates.…”

Section: Resultsmentioning

confidence: 97%

The Antimicrobial Properties Of Extracts Obtained From Begonia Goegoensis N.E.Br. Leaf Against Pseudomonas Aeruginosa Isolates

Tkachenko¹,

Osadowski²,

Buyun³

2017

Agrobiodiversity for Improving Nutrition, Health and Life Quality

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The present study was designed to evaluate the antibacterial property of crude extracts of the leaves of Begonia goegoensis N.E.Br. prepared in different solvent systems against Pseudomonas aeruginosa (ATCC 27583) and β-lactamases producing Pseudomonas aeruginosa (MBL-positive Pseudomonas aeruginosa) strains. Therefore, five kinds of solvents were used to extract the active ingredients from the leaves of Begonia goegoensis: ethanol, methanol, ethyl acetate, hexane, and dichloromethane. The testing of antibacterial activity of the plant extracts was carried out in vitro by Kirby-Bauer disc diffusion technique. Subsequently, the present study has shown that ethanolic extract from the leaves of Begonia goegoensis exhibited strong activity against Pseudomonas aeruginosa (inhibition zone diameter ranged from 12 mm to 13 mm), while methanolic leaf extract screened revealed less profound activity (within 11-12.5 mm). Moreover, it has been observed that ethyl acetate, hexane and dichloromethane extracts obtained from leaves of Begonia goegoensis revealed no antibacterial activity against P. aeruginosa and MBL-positive Pseudomonas aeruginosa strains. MBL-positive Pseudomonas aeruginosa was also susceptible to ethanolic and methanolic extracts (inhibition zone diameter ranged from 12.5 mm to 15.5 mm). Thus, the spectrum of activity observed in the present study indicate that the alcoholic leaf extract of Begonia goegoensis could be a possible source to obtain new and effective herbal medicines to treat various infectious diseases, including infections, caused by drug resistant microorganisms.

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“…The tubes containing the antimicrobial agent in concentration sufficient to inhibit the growth remaining clear. In experimental terms, the MIC is the concentration of the drug present in the last clear tube, i.e., the tube having the lowest antibiotic concentration in which growth is not observed (Ramesh 2002).…”

Section: Antibacterial Screeningmentioning

confidence: 99%

Design, synthesis, and docking studies of novel ofloxacin analogues as antimicrobial agents

et al. 2011

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A number of novel ofloxacin analogues were synthesized by modifying the carboxylic acid at C-6. To investigate the antimicrobial data on structural basis, in-silico docking studies of the tested compounds into the crystal structure of topoisomerase II using Autodock vina 4.0 program was performed in order to predict the affinity and orientation of the synthesized compounds at the activities. R 2 values show good agreement with predicted binding affinities obtained by molecular docking studies. Also, it is verified by in-vitro antimicrobial screening, where all the compounds were most active against Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis. Among these compounds 3a, 3b, 3f showed good MIC (0.125 lg/ml).

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Phytochemical and antimicrobial studies of Begonia malabarica

Cited by 42 publications

References 5 publications

Antibacterial potential from Indian Suregada angustifolia

Antibacterial potential from Indian Suregada angustifolia

The Antimicrobial Properties Of Extracts Obtained From Begonia Goegoensis N.E.Br. Leaf Against Pseudomonas Aeruginosa Isolates

Design, synthesis, and docking studies of novel ofloxacin analogues as antimicrobial agents

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