Phytochemical and antimicrobial activities of the Daniellia oliveri leaves

Ahmadu, AA; Haruna, Abdurrashid; Garba, M.; Ehinmidu, JO; Sarker, Satyajit D.

doi:10.1016/j.fitote.2004.01.019

Cited by 21 publications

(21 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The bark extract is used traditionally for control of gastro-intestinal parasites [11] , while the decoction of the root extract with other plant extracts is used in some parts of Southern Nigeria as remedy for hyperglycemia [12] . The leaf extract has been reported for its in vitro antioxidant potential [13] , antimicrobial activities [14] , [15] , in vivo anti-typhoid potential [16] and effect on skeletal muscles of experimental animals [17] . The resinous exudate obtained from the bark of the plant is used for wound healing purposes in Nigeria [18] .…”

Section: Introductionmentioning

confidence: 99%

Isolation and evaluation of antiglycation potential of polyalthic acid (furano-terpene) from Daniella oliveri

Atolanı

Olatunji

2014

Journal of Pharmaceutical Analysis

View full text Add to dashboard Cite

A furano-diterpene (polyalthic acid) was isolated as a major stable compound for the first time from the oleoresin of the Daniella oliveri of the family Caesalpiniacea through column chromatography fractionation. Polyalthic acid was characterized using data obtained from EIMS, HREIMS, ESI-MS, MALDI-MS as well as 1D and 2D NMR and it was evaluated for its potential to inhibit the formation of advanced glycation end-products (AGEs) using a standard in vitro antiglycation procedure. Polyalthic acid indicated a negative antiglycation potential compared to standard inhibitor that has 85% inhibition, which is an indication that polyalthic acid may not contribute to the antiglycation activity of the plant as acclaimed in folkloric medicine. The negative antiglycation observed could indicate that the polyalthic acid could trigger glycation, thereby subjecting users to various degrees of complications. The bioactivity evaluation on molinspiration evaluator indicated that polyalthic acid could be a potential drug candidate. The biological and chemical insights gained on polyalthic acid provide a good basis for future research.

show abstract

Section: Introductionmentioning

confidence: 99%

Isolation and evaluation of antiglycation potential of polyalthic acid (furano-terpene) from Daniella oliveri

Atolanı

Olatunji

2014

Journal of Pharmaceutical Analysis

View full text Add to dashboard Cite

show abstract

“…The n-butanol soluble part and four fractions of the aqueous ethanol extract of the leaves of Daniellia oliveri (Rolfe) Hutch & Dalziel (Fabaceae) were active against the fungus Trichophyton rubrum, 52 while the aqueous extract from the plant P. dodecandra (Phytolaccaceae) showed fungicidal activity against dermatophytes. 53 The seeds of two Apiaceae species, Ligusticum hultenii Fernald and Lomatium californicum (Nutt.)…”

Section: Crude Extractsmentioning

confidence: 99%

Active antifungal substances from natural sources

Abad¹,

Ansuategui²,

Bermejo³

2006

Arkivoc

View full text Add to dashboard Cite

The spread of multidrug-resistant strains of fungus and the reduced number of drugs available, makes it necessary to discover new classes of antifungals and compounds that inhibit these resistant mechanisms. This has led to a search for therapeutic alternatives, particularly among medicinal plants and compounds isolated from them used for their empirically antifungal properties. In these natural sources, a series of molecules with antifungal activity against different strains of fungus have been found, which are of great importance to humans and plants. In this article, we review the main sources of molecules with antimycotic activity obtained from the natural environment.

show abstract

“…Boswellia ovalifoliolata plant organs are known to be an important source of secondary metabolites, Ethiopian people are using the leaves to treat inflammation Boswellia ovalifoliolata plant organs are notably phenolic compounds [19]. Boswellia ovalifoliolata exhibited significant antimicrobial activity and showed properties that support folkloric use in the treatment of some diseases as broad-spectrum antimicrobial agents [20]. Thus, Boswellia ovalifoliolata is well anchored in its traditional uses has now found wide-spread acceptance across the world.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical, Antimicrobial Potential and Antifungal Activities Stem Bark Extract of Boswellia Ovalifoliolata

Gebregiorgis¹

2018

AOICS

View full text Add to dashboard Cite

This study was carried out with an objective to investigate the antibacterial and antifungal potentials of Stem bark of Boswellia ovalifoliolata (BO). The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of ethanolic extracts of stem bark of Boswellia ovalifoliolata. (Endemic medicinal plant) was evaluated for potential antimicrobial activity against medically important bacterial and fungal strains. The antimicrobial activity was determined in the extracts using agar disc diffusion method. The antibacterial and antifungal activities of extracts (5, 25, 50, 100, 250μg/ml) of Boswellia ovalifoliolata. Were tested against two Gram-positive Staphylococcus aureus, Streptococcus pyogenes two Gram-negative-Escherichia coli, Pseudomonas aeruginosa human pathogenic bacteria. Three fungal strains Aspergillus niger, Aspergillus clavatus, Candida albicans. Zone of inhibition of extracts were compared with that of different standards like ampicillin, ciprofloxacin, norfloxacin, and chloramphenicol for antibacterial activity and nystatin and griseofulvin for antifungal activity. The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The phytochemical analyses of the plants were carried out. The microbial activity of the Boswellia ovalifoliolata was due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.

show abstract

Phytochemical and antimicrobial activities of the Daniellia oliveri leaves

Cited by 21 publications

References 5 publications

Isolation and evaluation of antiglycation potential of polyalthic acid (furano-terpene) from Daniella oliveri

Isolation and evaluation of antiglycation potential of polyalthic acid (furano-terpene) from Daniella oliveri

Active antifungal substances from natural sources

Phytochemical, Antimicrobial Potential and Antifungal Activities Stem Bark Extract of Boswellia Ovalifoliolata

Contact Info

Product

Resources

About