Phytochemical And Antibacterial Activityof Leave Extracts Of Guiera Senegalensis Lam On Selected Species Of Gram Positive And Gram Negative Bacteria

Abstract

The aim of this study was to determine the preliminary phytochemical component and antibacterial activity of the leaves extract of Guiera senegalensis lam (Combretaceae) against three clinical isolates (Staphylococcus aureus, E. coli and Klebsiella species) using standard method of analysis. The test for phytochemical component revealed the presence of alkaloid, anthraquinolones, tannin and phlobatanins. The result of antibacterial activity showed that the ethanolic extract exhibit higher zone of inhibition against all the clinical isolates, with E. coli and Klebsiella species showed zone of inhibition of 35mm followed Staphylococcus aureus 30mm. Similarly, both aqueous and methanolic extract were sensitive to all the clinical isolate except Klebsiella species which showed resistance to the methanolic extract of the leaves. The results obtained in this research imply that the leaves extract of Guiera senegalensis lam could be useful in the treatment of infections caused by Staphylococcus aureus, E. coli and Klebsiella species.

Ethnobotanical survey of medicinal plants used for traditional maternal healthcare in Katsina state, Nigeria

“…Although many plants were reported to cure nausea, vomiting and diarrhea, G. senegalensis had a FL of 100% for these ailments, indicating consensus among all of the respondents who cited G. senegalensis; thus, this plant appeared to be the most important plant species identified in this study. Many studies (Yagana et al, 2012;Djifaby et al, 2012;Mamman and Isa, 2013; Sombié et al, 2013) support the use of G. senegalensis for antimicrobial activities. Kim and Lean (2013), however, reported that Anastatica hierochuntica L. is the most common herb used by pregnant women in Malaysia.…”

Revue bibliographique sur la composition chimique et les activités biologiques de <i>Guiera senegalensis</i> J.F. Gmel. (Combretaceae)

“…Le criblage phytochimique des extraits de feuilles, de racines, de tiges et de galles a montré la présence d'hydrates de carbone, de stéroïdes, de saponines, de flavonoïdes, d'alcaloïdes, de tanins, de saponines, de glycosides cardiaques, de coumarines, d'anthraquinones, d'acide ascorbique, d'hétérosides cardiotoniques, de cyanogènes et de terpénoides (Sule et al, 2001;Lamien et al, 2005;Williams et al, 2009;Sombié et al, 2011;Somboro et al, 2011;Mamman et Isa, 2013;Salihu et Usman, 2015;Al Shafei et al, 2016;Biu et al, 2016). Mariod et al (2016) ont déterminé, selon la procédure de Folin-Ciocalteu et calculée en équivalents d'acide gallique (EAG), les teneurs en composés phénoliques totaux dans les extraits de feuilles.…”

“…Toujours au Nigeria, Mamman et Isa (2013) ont montré dans leur étude que Staphylococcus aureus, E. coli et Klebsiella étaient sensibles à l'extrait éthanolique des feuilles de G. senegalensis (Mamman et Isa, 2013). Djifaby et al (2012) du Burkina Faso ont observé dans leur étude que les extraits de feuilles possèdent une activité inhibitrice contre Bacillus cereus ATCC 13061 et Staphylococcus aureus ATCC 6538 qui présentaient une résistance à la pénicilline et à l'ampicilline.…”

An academic review of the first two volumes of the International Journal of Environment (IJE)

“…The areas of weaknesses were lack of tourism infrastructures and services, lack of tourist information and weak management of tourist area. Mamman and Isa (2013) conducted experiments to determine the preliminary phytochemical component and antibacterial activity of the leaves extract of Guierasenegalensis lam (Combretaceae) against three clinical isolates (Staphylococcus aureus, E. coli and Klebsiella species) using standard method of analysis. This study revealed that the leaves extract of Guierasenegalensis lam could be useful in the treatment of infections caused by Staphylococcus aureus, E. coli and Klebsiella species Bhandari (2013) analysed the trend of rainfall and temperature and their effect on the yield of major cereals Paddy/rice (Oryzasativa L.), wheat (Triticumaestivum L.), maize (Zea mays L.), millet (Eleusinecoracana Gaertn.)…”