Phytochemical and Antibacterial Activities of Ocimum Gratissiumum L. on Isolates from Kunu-Zaki

Abstract

This study involved a comprehensive analysis of phytochemical components of the aqueous extract of Ocimum gratissimum which revealed ascorbic acid to be the most abundant component, followed by tannins and flavonoids, while alkaloids, phytate, and cardiac glycosides were found in minimal amounts, while the ethanolic extract revealed the high components of ascorbic acid followed by flavonoid then tannin while other components were recorded in minimial amount. The study also evaluated the antibacterial properties of Ocimum gratissimum L. (scent leaf) against bacteria isolated from Kunu-zaki. Gram-negative organisms exhibited sensitivity to Gentamicin, Augmentin, and Ciprofloxacin, but demonstrated resistance to erythromycin, tetracycline, amoxicillin, ampicillin, and chloramphenicol.In contrast, gram-positive organism displayed sensitivity to Rocephin, Streptomycin, Pefloxacin, Ciprofloxacin, Gentamicin, and Zinnacef. Furthermore, the study examined the antimicrobial susceptibility of Ocimum gratissimum aqueous and ethanolic extracts on the isolated bacteria, the ethanolic extract yielded more favorable results, while ciprofloxacin was used as a control.