Phytochemical analysis of the hot tea infusion of Hedyosmum brasiliense

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

“…This is enabled by the availability of the digital NMR raw data. This approach has been used by Lima et al (2015 and 2016),241,242 Pederoso et al (2008),243 Amoah et al (2015),244 and da Silva et al (2015),245 for establishing the connectivity of aromatic and side chain moieties of several NPs. In the case of butein ( 100 ),242 for example, the shifted sinebell multiplication (SINM) followed by an exponential multiplication (EM) of the FID with a Lorentzian line broadening factor of 0.3 Hz instead of the simple EM (default setting on most NMR spectrometers; see also Fig.…”

Ethnopharmacology, phytochemistry and pharmacology of the genus Hedyosmum (Chlorantaceae): A review

“…The mentioned compound was previously separated from other plant species, such as Xylopia brasiliensis (Moreira et al, 2003). Amoah et al (2013a;2015b) reported eudesmane sesquiterpene lactones 1-α-acetoxyeudesma-3,7(11)-dien-8,12-olide and 15-hydroxy-isogermafurenolide from H. brasiliense. The sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide was also identified in a hydroalcoholic extract obtained from stems and leaves of H. brasiliense (Trentin et al, 1999;Calixto et al, 2001).…”

“…Additionally, Su et al (2008) reported the presence of spathulenol and other sesquiterpenes, such as 13-hydroxy-8,9-dehydroshizukanolide and aromadendrane-4β,10β-diol, in the ethanolic extract of the aerial parts of H. orientale. The sesquiterpene alcohol aromadendrane-4β,10α-diol was obtained from the leaves of H. brasiliense by Amoah et al (2013a and2015b). The mentioned compound was previously separated from other plant species, such as Xylopia brasiliensis (Moreira et al, 2003).…”