Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of <i>Phytolacca dodecandra</i> L. Herit Leaf Extracts (Phytolaccaceae)

Abstract

From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC 50 ) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture.

Effects of genotype and Phytolacca dodecandra (Endod) supplementation on growth performance, carcass traits, blood profiles, and breast meat quality of chickens

“…According to the findings presented in Table 2 , the plant being studied in the current investigation contains a range of bioactive compounds such as saponins, tannins, flavonoids, and alkaloids, which is in agreement with the results reported by Ref. [ 33 ]. Our study indicates that both diet and genotype * diet interactions significantly affect the growth performance of chicks.…”

“…The use of medicinal plants in animal feeds has gained much attention in recent years due to its potential to enhance growth performances [ 32 ]. The active components present in Phytolacca dodecandra , also known as Phytolacca dodecandra (Endod) or Ethiopian soapberry, have various physiological and biochemical functions in the body [ 33 ]. According to the findings presented in Table 2 , the plant being studied in the current investigation contains a range of bioactive compounds such as saponins, tannins, flavonoids, and alkaloids, which is in agreement with the results reported by Ref.…”

Synthesis of Cu doped NiO for Their Antioxidant and Photocatalytic Properties: Green Synthesis Using Lycopodium Linn

“…In plants, phenols are the most widespread secondary metabolites. They are recommended for use in the treatment of many illnesses due to their high antioxidant content and other bene cial biological features [42]. The photocatalytic degradation mechanism of MB on Cu doped NiO is shown schematically in Fig.…”

TLC Profiling of Leaves Extracts of Some Aloe Threatened Species Endemic to Madagascar for Their Antioxidant Activity

“…In fact, the excess production of Oxygen Reactive Species (ORS) can become toxic to the major components of the cell and gives rise to oxidative stress, which will lead to numerous pathologies such as neurodegenerative diseases (Alzheimer, Parkinson), diabetes, cancer, inflammatory diseases, aging, etc. Cells use many antioxidant strategies to eliminate or minimize the oxidative damage (Iteku et al, 2019). These plants contain an arsenal of bioactive compounds like coumarins, flavonoids, terpenoids, alkaloids, tannins, etc.…”