Phytic acid increases mucin and endogenous amino acid losses from the gastrointestinal tract of chickens

Onyango, E. M.; Asem, Elikplimi K.; Adeola, O.

doi:10.1017/s0007114508047740

Cited by 54 publications

(27 citation statements)

References 30 publications

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“…The basis for this unanticipated effect is unclear, but ≥1 of the following may be involved: improved iron absorption, inositol release, or amino acid release. Phytic acid inhibits protein solubility (97) and increases endogenous mucin amino acid loss (98). …”

Section: Current Status Of Knowledge: Findings From Animal Science Rementioning

confidence: 99%

The Potential Impact of Animal Science Research on Global Maternal and Child Nutrition and Health: A Landscape Review

Odle

Jacobi

Boyd

et al. 2017

Advances in Nutrition

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High among the challenges facing mankind as the world population rapidly expands toward 9 billion people by 2050 is the technological development and implementation of sustainable agriculture and food systems to supply abundant and wholesome nutrition. In many low-income societies, women and children are the most vulnerable to food insecurity, and it is unequivocal that quality nutrition during the first 1000 d of life postconception can be transformative in establishing a robust, lifelong developmental trajectory. With the desire to catalyze disruptive advancements in global maternal and child health, this landscape review was commissioned by the Bill & Melinda Gates Foundation to examine the nutritional and managerial practices used within the food-animal agricultural system that may have relevance to the challenges faced by global human health. The landscape was categorized into a framework spanning 1) preconception, 2) gestation and pregnancy, 3) lactation and suckling, and 4) postweaning and toddler phases. Twelve key findings are outlined, wherein research within the discipline of animal sciences stands to inform the global health community and in some cases identifies gaps in knowledge in which further research is merited. Notable among the findings were 1) the quantitative importance of essential fatty acid and amino acid nutrition in reproductive health, 2) the suggested application of the ideal protein concept for improving the amino acid nutrition of mothers and children, 3) the prospect of using dietary phytase to improve the bioavailability of trace minerals in plant and vegetable-based diets, and 4) nutritional interventions to mitigate environmental enteropathy. The desired outcome of this review was to identify potential interventions that may be worthy of consideration. Better appreciation of the close linkage between human health, medicine, and agriculture will identify opportunities that will enable faster and more efficient innovations in global maternal and child health.

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Section: Current Status Of Knowledge: Findings From Animal Science Rementioning

confidence: 99%

The Potential Impact of Animal Science Research on Global Maternal and Child Nutrition and Health: A Landscape Review

Odle

Jacobi

Boyd

et al. 2017

Advances in Nutrition

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“…Analyzing the average egg production obtained with 13, 15, and 17% CP with phytase addition, we observed lowest egg production in the treatment containing 13% CP, which might have induced the average of the other treatments (17 and 15%) to be lower than those of treatments without phytase addition. In this case, the low dietary CP level (13%) could not be offset by phytase addition (Onyango, Asem, & Adeola, 2009).…”

Section: Resultsmentioning

confidence: 87%

<b>Phytase in diets with crude protein levels for commercial layers

Pereira

Junqueira

Júnior

et al. 2017

Acta Sci. Anim. Sci.

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ABSTRACT. The aim of this study was to evaluate the action of the phytase enzyme in diets formulated with variations in the crude protein content on performance and egg quality of commercial layers. A total of 336 commercial layers were housed at eight birds per cage in a 3 × 2 factorial arrangement with seven replicates. Treatments consisted of four crude-protein levels (17, 15, and 13%) and two enzyme levels (0 and 500 FTU kg -1 diet), distributed in a completely randomized design. Feed intake, egg production, feed conversion per dozen eggs and per kilogram, egg weight and mass, specific gravity, eggshell thickness, and Haugh unit were measured over five 28-day periods. The performance of commercial layers fed the diet containing 13% crude protein worsened, irrespective of phytase addition. However, at 15% crude protein, phytase inclusion did not affect feed conversion or egg weight. Inclusion of phytase leads to equal egg-quality and performance results at the dietary crude protein levels of 17 and 15%. The crude protein content of 13%, with or without phytase, is not recommended for the diet of brown-egg layers.Keywords: phosphorus, chicken, nitrogen, eggs.Fitase em rações com níveis de proteína bruta para poedeiras comerciais RESUMO. Objetivou-se avaliar a ação da enzima fitase em rações formuladas com variação na proteína bruta sobre o desempenho e a qualidade de ovos de poedeiras comerciais. Foram alojadas 336 poedeiras comerciais, em esquema fatorial 3 x 2, com sete repetições e oito aves em cada gaiola. Os tratamentos constituíram de três níveis de proteína bruta (17, 15 e 13%) e dois níveis da enzima fitase (0 e 500 FTU kg -1 ração), distribuídos em delineamento inteiramente casualizado. Durante cinco períodos, de 28 dias cada, foram avaliados o consumo de ração, a produção de ovos, a conversão alimentar por dúzia e por quilograma, o peso e a massa de ovos, a gravidade específica, a espessura de casca e a unidade Haugh. Constatou-se piora no desempenho das poedeiras comerciais alimentadas com 13% de proteína bruta na ração, independente da adição da fitase. Porém, em 15% de proteína bruta, a inclusão da fitase não afetou a conversão alimentar e o peso dos ovos das aves. A inclusão da fitase proporciona resultados de qualidade de ovos e desempenho iguais para os níveis de 17 e 15% de proteína bruta na ração. Não se recomenda o nível de 13% de proteína bruta, com ou sem fitase, na ração de poedeiras semipesadas.

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“…Forty‐eight birds with close‐ranging weights were selected and grouped into eight blocks of six cages each with one bird per cage. All methods and procedures used in this study were approved by the Purdue University Animal Care and Use Committee, and they were as described in our previous study on chicken (Onyango et al., 2009) and are summarized herebelow. Factorial arrangement of two dietary factors, IP6 form (no IP6, 2.0 g free phytic acid or 2.6 g magnesium‐potassium phytate), and phytase (0, or 1000 units), was employed to obtain six dextrose‐based dietary treatments: dextrose (25 g) alone; dextrose plus either free phytic acid, magnesium‐potassium phytate, 1000 units of phytase (Phyzyme XP; Danisco Animal Nutrition, Marlborough, Wiltshire, UK), free phytic acid with phytase, or magnesium‐potassium phytate with phytase.…”

Section: Methodsmentioning

confidence: 99%

“…The six dietary treatments were randomly assigned to cages within a block (randomized complete block design). Feed was withdrawn from the birds for 24 h. At the end of the 24‐h fast, birds were fed by intubation the assigned dextrose‐based combinations, and for the next 54 h, excreta were collected and frozen until further processing as previously described (Onyango et al., 2009).…”

Section: Methodsmentioning

confidence: 99%

“…For example, IP6 has been reported to inhibit a variety of digestive enzymes possibly by forming IP6‐protein complexes, thus making them less effective in the digestive process (Jenab and Thompson, 2002). We have shown in our recent study that the form of IP6 fed to chickens affects the extent of the increase in mucin excretion caused (Onyango et al., 2009). Our study also confirmed what Cowieson et al.…”

Section: Introductionmentioning

confidence: 98%

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Inositol hexaphosphate increases mucin loss from the digestive tract of ducks

Onyango

Adeola

2011

Animal Physiology Nutrition

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The effects of different forms of inositol hexaphosphate (IP6, phytate) on mucin excretion from the digestive tract of ducks were investigated. Forty-eight ten-wk-old male ducks were grouped by weight into eight blocks of six cages with one bird per cage. On the first day of experimentation, birds received by intubation six dextrose-based diets arranged in a 2 × 3 factorial consisting of phytase (0 or 1000 units) and a form of IP6 (no IP6, free phytic acid or magnesium-potassium phytate). During the 54 h following feeding, excreta were continuously collected and frozen until analysed. The amount of mucin and amino acids, threonine, valine and tyrosine, in excreta increased in ducks fed with either magnesium-potassium phytate or free phytic acid. The increase in mucin excretion was more in birds fed with magnesium-potassium phytate than those fed with free phytic acid. The loss of arginine, isoleucine, leucine, lysine and phenylyalanine in excreta was reduced by the presence of microbial phytase. It is concluded that the form of IP6 fed to ducks affects the extent of mucin excretion and also the extent and nature of endogenous amino acid losses in the excreta. Supplementation with exogenous microbial phytase reduced some of the IP6 feeding-induced endogenous intestinal amino acid losses.

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Phytic acid increases mucin and endogenous amino acid losses from the gastrointestinal tract of chickens

Cited by 54 publications

References 30 publications

The Potential Impact of Animal Science Research on Global Maternal and Child Nutrition and Health: A Landscape Review

The Potential Impact of Animal Science Research on Global Maternal and Child Nutrition and Health: A Landscape Review

<b>Phytase in diets with crude protein levels for commercial layers

Inositol hexaphosphate increases mucin loss from the digestive tract of ducks

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