“…However, their transport dependence on extracellular [Na + ], [K + ], and [Cl − ] was studied by different research groups and found to be consistent with a one ion‐binding site model for each cation and a two ion‐binding site model for Cl − (Gagnon et al, 2004; Gagnon, Forbush, Caron, & Isenring, 2003; Gimenez & Forbush, 2007; Gimenez, Isenring, & Forbush, 2002). It should be nonetheless remembered that such models were inferred from Hill coefficients and that they thus only provide an estimate of the minimal number of binding sites involved (Garneau et al, 2017; Garneau, Marcoux et al, 2019; Garneau, Slimani et al, 2019; Marcoux et al, 2017).…”