2004
DOI: 10.2170/jjphysiol.54.93
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Physiological Regulation of Renal Sodium-Dependent Phosphate Cotransporters

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Cited by 62 publications
(51 citation statements)
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“…The phosphaturic effect observed at elevated serum levels of FGF-23 correlated with a decrease of the abundance of NaPi-lla and NaPi-llc [79,80]. Moreover, FGF23…”
Section: Phosphatoninsmentioning
confidence: 92%
“…The phosphaturic effect observed at elevated serum levels of FGF-23 correlated with a decrease of the abundance of NaPi-lla and NaPi-llc [79,80]. Moreover, FGF23…”
Section: Phosphatoninsmentioning
confidence: 92%
“…Renal regulation of NaPi-IIa has been the subject of extensive reviews (Murer, Hernando et al 2000;Werner&Kinne 2001;Tenenhouse&Murer 2003;Miyamoto, Segawa et al 2004;Tenenhouse 2005;Forster, Hernando et al 2006). The regulation of P i reabsorption centers on controlling the number of transporter proteins in the proximal tubule brush border membrane.…”
Section: Fig 1 Near Herementioning
confidence: 99%
“…Consistent with electroneutral cotransport of divalent P i , it has been proposed that NaPi-IIc cotransports with a 2:1 Na ϩ ͞HPO 4 2Ϫ stoichiometry (2,10). It follows that NaPi-IIc may lack one of the three Na ϩ binding sites postulated for NaPi-IIa.…”
mentioning
confidence: 93%
“…Two isoforms of type II Na ϩ -coupled P i cotransporters (NaPi-II), both localized at the proximal tubule apical brush border membrane, have been identified. Both cotransporters mediate inward transport of P i by using the inwardly directed Na ϩ gradient (1,2). Type IIa cotransporters (SLC34A1 or NaPi-IIa) couple three Na ϩ ions to the cotransport of one divalent P i ion, and each transport cycle is accompanied by the inward translocation of one net positive charge (3,4).…”
mentioning
confidence: 99%