“…They are an important construction material for the preparation of soluble polymeric carriers, micelles, liposomes, (polymer-coated) nanoparticles, and polyplexes. [1][2][3][4] The most important applications of such polymers are to increase solubility of the systems in aqueous environment, to anchor targeting groups, to ensure responsiveness to external stimuli (e.g., to changes in pH or temperature) and to increase biocompatibility or non-immunogenicity of the whole system. Decreasing immunogenicity of the conjugate may by essential for delivery of proteins from other organisms that are essentially immunogenic.…”