Physiological Consequences of Reduced Physical Activity During Bed Rest

Greenleaf, J. E.; Kozłowski, S

doi:10.1249/00003677-198201000-00004

Cited by 99 publications

(63 citation statements)

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“…1,2,[8][9][10][11] The major consequences to the respiratory system include development of compression atelectasis from the formation of dependent edema with the patient supine and impaired ability to clear the lungs because the normal lung-clearing functions of the mucociliary escalator, cough reflex, and drainage do not work as well with the patient supine. This impaired clearing places immobilized patients at greater risk for VAP or hospital-acquired pneumonia.…”

Section: System-specific Changesmentioning

confidence: 99%

“…This impaired clearing places immobilized patients at greater risk for VAP or hospital-acquired pneumonia. 8,10,11 The changes in the cardiovascular system related to bed rest are significant. The act of lying down shifts 11% of the total blood volume away from the legs, with most going to the chest.…”

Section: System-specific Changesmentioning

confidence: 99%

“…This loss stabilizes to 15% to 20% by the fourth week of bed rest. 1,[8][9][10][12][13][14] The result is an increase in cardiovascular workload, elevation of resting heart rate, and a decrease in stroke volume with a reduction in cardiac output. Orthostatic tolerance deteriorates rapidly with immobility.…”

Section: System-specific Changesmentioning

confidence: 99%

“…ICU-acquired weakness is caused by many factors: the inflammatory response, glycemic control, use of myotoxic or neurotoxic medications like corticosteroids or neuromuscular blocking agents, and immobility. 1,[8][9][10] Immobility in critically ill patients leads to decreased protein synthesis in muscle, increased catabolism of the muscle, and decreased muscle mass that is more pronounced in the lower limbs. [17][18][19] Muscle groups that lose the most strength are involved in maintaining posture, transferring activities, and ambulation.…”

Section: System-specific Changesmentioning

confidence: 99%

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Introduction to Progressive Mobility

Vollman¹

2010

Critical Care Nurse

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Section: System-specific Changesmentioning

confidence: 99%

Section: System-specific Changesmentioning

confidence: 99%

Section: System-specific Changesmentioning

confidence: 99%

Section: System-specific Changesmentioning

confidence: 99%

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Introduction to Progressive Mobility

Vollman¹

2010

Critical Care Nurse

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“…Although rest is an effective way of reducing tiredness and brings symptom relief in the short term, in the long term it is not helpful as it reduces exercise tolerance and can produce increased weakness, muscle wasting, and cardiac and respiratory difficulties, together with increased sensitivity to activity (Greenleaf and Kozolowski, 1982). Following an extended period of rest (days, weeks or months), any activity produces a range of associated symptoms.…”

Section: Description Of Daily Patterns Of Activitymentioning

confidence: 99%

Chronic Fatigue Syndrome – an occupational therapy programme

Cox

1999

Occupation Therapy Intl

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Strategies for managing cancer-related fatigue syndrome

Winningham¹

2001

Cancer

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Although technologic advances and insights into the mechanisms of cancer and cancer treatments have resulted in hope of increased survival and even cure in many cancer populations, parallel efforts to promote quality of life through a commitment to rehabilitation and aggressive palliation have lagged. Recent studies have demonstrated fatigue to be the most distressing phenomenon experienced by cancer patients. This article examines fatigue from a rehabilitation perspective. Application of innovations in therapeutic exercise training, diet therapy, sleep therapy, cognitive therapy, and pharmacologic therapy and their attendant rationales are discussed. From clinical as well as research perspectives of palliation and rehabilitation, the manifestations of fatigue are better appreciated if fatigue is conceptualized as a syndrome, namely, cancer‐related fatigue syndrome (CRFS). Experience of CRFS by cancer patients, regardless of their diagnosis, stage of disease, treatment regimen, or age, influences all aspects of quality of life and aggravates the experience of other distressing symptoms such as pain, nausea, and dyspnea. Understanding the underlying mechanisms for energy loss and gain, as well as the relationship between the right amount and type of activity and sleep, can lead toward more effective and innovative rehabilitation programs. Development of research based clinical interventions in these areas holds promise for significant improvement in functioning and quality of life for cancer survivors and may constitute valuable rehabilitative techniques that can be adjunctive to standard therapies. Cancer 2001;92:988–97. © 2001 American Cancer Society.

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Physiological Consequences of Reduced Physical Activity During Bed Rest

Cited by 99 publications

References 0 publications

Introduction to Progressive Mobility

Introduction to Progressive Mobility

Chronic Fatigue Syndrome – an occupational therapy programme

Strategies for managing cancer-related fatigue syndrome

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