Physiologic Response of Ventilator-dependent Patients with Chronic Obstructive Pulmonary Disease to Proportional Assist Ventilation and Continuous Positive Airway Pressure.

Respiratory muscle workload in intubated, spontaneously breathing patients without COPD: pressure support vs proportional assist ventilation

“…PTP is often used to investigate patient-machine interactions [19]. Various studies have shown a decrease in WOB and/or PTP during PAV compared to spontaneous breathing [6,18,20]. However, when PAV is compared to PSV with regard to WOB, only two studies documented a decrease in WOB during PAV [5,12].…”

Bedside Adjustment of Proportional Assist Ventilation to Target a Predefined Range of Respiratory Effort*

“…However, because tidal volume is chosen by the patient on a breath-by-breath basis (23) and the insufflation time is close to the neural inspiratory time (23,32) whatever the level of assistance (16), the risk of significant dynamic hyperinflation is low in PAV-I- (22). Eurthermore, Appendini et al ( 15) showed that adding continuous positive airway pressure during proportional assist ventilation dramatically reduced the level of PEEPi in chronic obstructive pulmonary disease (COPD) patients with a high basal level of PEEPi. In our study, only three patients were intubated because of an acute exacerbation of a COPD.…”

“…From this estimation ofthe PTP_^^^, we considered that with usual values of Ti and RR (15)(16)(17)(18), targeting a P^^^p^^^. between 5 and 10 cm H,0 should allow the PTP to remain between 50 2 mus and 150 cm H^O-s/min.…”

Neue Wege in der Beatmungstherapie

“…Im günstigsten Fall kann die Atemarbeit des Patienten durch die Respiratoreinstellung (Kombination von PSV und PEEP) um ca. 75 % reduziert werden [29]. Der Exspirationsdruck sollte zu Beginn der NIV niedrig bei ca.…”