We consider extended scalar sectors of the Standard Model as ultraviolet-complete motivations for studying the effective Higgs self-interaction operators of the Standard Model effective field theory. We investigate all motivated heavy scalar models which generate the dimension-6 effective operator, |H| 6 , at tree level and proceed to identify the full set of tree-level dimension-six operators by integrating out the heavy scalars. Of seven models which generate |H| 6 at tree level only two, quadruplets of hypercharge Y = 3YH and Y = YH , generate only this operator. Next we perform global fits to constrain relevant Wilson coefficients from the LHC single Higgs measurements as well as the electroweak oblique parameters S and T . We find that the T parameter puts very strong constraints on the Wilson coefficient of the |H| 6 operator in the triplet and quadruplet models, while the singlet and doublet models could still have Higgs self-couplings which deviate significantly from the standard model prediction. To determine the extent to which the |H| 6 operator could be constrained, we study the dihiggs signatures at the future 100 TeV collider and explore future sensitivity of this operator. Projected onto the Higgs potential parameters of the extended scalar sectors, with 3 ab −1 luminosity data we will be able to explore the Higgs potential parameters in all seven models. arXiv:1705.02551v2 [hep-ph] 22 Nov 2017 2 An exception to this is the HS 3 or HS 2 vertex, however the HS 3 vertex will not generate operators at tree level below dimension-eight and the HS 2 vertex does not exist for any representations given the Higgs is a doublet of SU (2) L .