Physics and instrumentation

Myocardial imaging with extractable cations and inert tracers: The effects of flow and metabolism

“…Close co-operation between clinicians and physicists is required to understand the physical determinants of the data recorded (5). The heart to background ratio, the overall resolution of edges, the effects of attenuation, scatter, respiration and hea rt movement are a few of the physical factors that must be considered (4,16,30).…”

“…The gamma camera allows both spatial and temporal resolution in images and rapid accumulation of data. It provides the technology necessary for the non-invasive assessment of clinical problems in patients with coronary artery disease (5). These problems involve the identification and investigation of the pathophysiology of coronary artery stenosis, reversible disturbances of regional myocardial perfusion, permanent disturbances such as myocardial infarction and fibrosis and finally the effects of medical therapies and coronary artery surgery.…”

Comparison of single plane and biplane radionuclide ventriculograms performed in oblique projections in patients with acute myocardial infarction.

“…Radionuclide ventriculography was carried out using a computerised multi-crystal gamma camera (Baird-Atomic, system 77) with high count rate capabilities (Budinger and Rollo, 1977). Studies were performed using a 1'5-inch parallel hole collimator.…”

PET-based imaging to detect and characterize cardiovascular disorders: Unavoidable path for the foreseeable future

“…4,5 The concept of tomographic imaging by using an Anger camera was introduced by investigators at the University of Michigan and Berkley, which led to adopting emission tomography as a powerful modality in the practice of medicine. 6,7 Currently, single-photon emission computed tomography (SPECT) is the workhorse of the specialty around the world. Unfortunately, SPECT imaging has suffered from the lack of progress in synthesizing novel tracers for research and clinical purposes.…”