Physicochemical studies on the catanionics of alkyltrimethylammonium bromides and bile salts in aqueous media

Physico-chemical Studies on the Interaction of Dendrimers with Lipid Bilayers. 1. Effect of Dendrimer Generation and Liposome Surface Charge

“…He-Ne laser emitting light at 632 nm was used. Size measurements were done using a quartz cell of 1.0 cm path length, while a specially designed plastic cell was used for zeta potential measurements 38 .…”

Solubilization power of an amino acid-based gemini surfactant towards the hydrophobic drug amphotericin B

“…Several factors can account for these results, which include the hydrophobic nature of the surfactants, micellar size and micellar shape [11,[24][25][26]44]. Bile salts are facial amphiphiles with weakly separated hydrophilic (carboxylate and hydroxyl groups) and hydrophobic (steroid backbone) moieties and the rigid steroid skeleton favours disk-like micelles [11,[44][45][46], where electrostatic interactions and surface charge density are reduced compared to spherical micelles. On the contrary, gemini surfactants with short alkyl side chains, including short-chain gemini surfactants derived from cysteine bearing a lipophilic disulfide bridge as spacer, such as (C 8 Cys) 2 , prefer to form spherical micelles [36,41].…”

“…The aggregation number of (C 8 Cys) 2 in water has been determined from fluorescence quenching measurements using pyrene as probe and a value of 20 has been obtained, corresponding to 40 hydrocarbon chains per micelle regarding the dimeric structure of the gemini surfactant [36]. Due to their characteristic amphiphilic structure, the bile salts form micelles with smaller aggregation numbers than conventional surfactants, in the range of 5-15 per micelle, and premicelle formation is frequent and characterized by formation of dimmers or small aggregates of 2-4 molecules [9,11,[43][44][45][46]. An aggregation number of about 15 has been referred for NaDC in water and also in NaOH 0.001 mol L −1 (pH 11) at 25 °C [43,47].…”

The mixing behaviour of anionic and nonionic surfactant blends in aqueous environment correlates in fatty acid ester medium

“…where, f 1 m and f 2 m are the activity coefficients of Tween-85 and AOT, respectively [55]. The f 1 m and f 2 m are found to be less than unity (Table 2) which signifies non-ideal mixing behavior favored by attractive interactions between Tween-85 and AOT.…”