Physicochemical properties, metabolomic analysis, antioxidant and lipid-lowering activity of a functional beverage based on cocona (Solanum sessiliflorum Dunal)

Abstract

The physicochemical, microbiological and metabolomics analysis, antioxidant and lipid-lowering effect, and shelf life prediction of a functional beverage based on cocona pulp of SRN9 ecotype was to carry out. According to the results obtained, the beverage complies with all the characteristics of the Peruvian technical standard for juices, nectars and fruit beverages NTP 203.110:2009 and is within the limits established by the sanitary technical standard NTS N° 071-MINSA/DIGESA-V.01, with a shelf-life period of 4 months and 1 day. The metabolome regarding bioactive compounds showed the presence of 30 compounds, including several glycosylated flavonols, two flavanols, and two spermidines. Likewise, showed a lipid-lowering effect statistically significant (p < 0.05) about the serum levels of total cholesterol and triglycerides, with a mean reduction of 41.52 mg/dL for total cholesterol levels and 130.80 mg/dL for triglyceride levels. This beverage could be an alternative for the treatment of atherosclerosis and prevention of cardiovascular diseases.