Cissus quadrangularis L., a succulent plant, is found throughout most of the world, but is particularly common in Asia, Africa, and some other warm tropical regions. Seedling#039; is a common food in India. The whole plant is used in Ayurveda as a digestive aid and sedative (Pachana).In addition, C. quadrangularis is rich in ascorbic acid, triterpenoids, flavonoids and carotenoids. Other properties of C. quadrangularis include antibacterial, analgesic, antiulcer, anthelmintic, antifungal, hemorrhoidal, and fracture healing.In addition, it is the best way to treat many diseases such as dyspepsia, dysentery, burns, hemorrhoids, diarrhea, bowel problems and epilepsy. The important pharmacological activities of plants, including their antioxidant, anti-inflammatory, anti-ulcer, antibacterial, anxiolytic, antipyretic, anti-diabetic, bone healing and phytochemical properties, are the focus of research summarized in this article. In this era of drug development and newer drug discovery; The molecules of many herbal products are evaluated based on their traditional uses. One of the many plants valued for its therapeutic efficacy is Cissus quadrangularis, commonly known as Hadjod (Bengali) and Edible Vine (English).