Physicochemical characterization of chitin extracted by different treatment sequences from an edible insect

Chalghaf, Manel; Charradi, Khaled; Ksouri, Riadh; Alsulami, Qana A.; Jaouani, Atef; Keshk, Sherif M.A.S.; Hayouni, El Akrem

doi:10.1016/j.ijbiomac.2023.127156

Cited by 7 publications

(3 citation statements)

References 41 publications

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“…According to our latest paper [26], two processing steps regular deproteinization (DEP) and Demineralization (DEM) were used to extract the chitin that also simultaneously removed proteins, fats, and color from the dried insect powder. Subsequently, from the dried extracted chitin preparation, 1 g was refl uxed within 60% NaOH solution for 4 h at 150 °C.…”

Section: Chitin Extraction and Chitosan Preparationmentioning

confidence: 99%

Punica granatum Bioactive Compounds-Loaded Chitosan Nanoparticles Exhibit Potent Antihyperglycemic Effect in Alloxan-Induced Diabetic Mice

Chalghaf,

Trifi,

Chirchi

et al. 2024

J Biomed Res Environ Sci

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In the current study, alloxan-induced diabetic mice model was used to assess the antihyperglycemic effects of Chitosan Nanoparticles (CSNP) loaded with (Punica granatum methanol extract-PG) bioactive compounds. Analysis of P. granatum extract revealed significant concentrations of various classes of polyphenols. In particular, the total polyphenols content is noted at 289.6 ± 5.1 mg/g, while flavonoids and anthocyanins exhibited concentrations of 53.7 ± 0.8 mg/g and 34.8 ± 0.4 mg/g, respectively. Chitosan nanoparticles were prepared by ionic gelation technique using TPP as crosslinking agent. Their spectroscopic characterization showed a good stability, high encapsulation efficiency and the bioactive molecule-loaded CNPs were well-dispersed with homogeneous distribution in the nanosolutions. In vivo experiments showed that when compared to the diabetic control group, diabetic mice treated with CSPG-CNP (100 mg/kg bw) displayed a significant decrease in their mean fasting blood glucose levels. Moreover, hepatic and kidneys histopathological examination showed clear improvements in hepatic alterations in animals treated with CSPG-CNP compared to diabetic control group. Indeed, hepatic cells regained normal size, hepatic steatosis decreased, and the number of inflammatory cells was drastically reduced, suggesting effectiveness of this combination in improving diabetes-induced hepatic lesions. Moreover, mice of CSPG-CNP group showed significant improvements in renal alterations with signs of renal tissue repair. Indeed, damage to Bowman's capsule, glomeruli, and renal tubules were improved, returning to normal renal histology.

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Section: Chitin Extraction and Chitosan Preparationmentioning

confidence: 99%

Punica granatum Bioactive Compounds-Loaded Chitosan Nanoparticles Exhibit Potent Antihyperglycemic Effect in Alloxan-Induced Diabetic Mice

Chalghaf,

Trifi,

Chirchi

et al. 2024

J Biomed Res Environ Sci

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“…Solid-state NMR allows for the investigation of materials tha readily dissolve in traditional liquid-state NMR solvents [28]. As shown in Tab Figure 7, there are some specific peaks and their approximate chemical shifts in NMR spectra of chitin and chitosan [59,64,69,[107][108][109]…”

Section: Nuclear Magnetic Resonance Spectroscopymentioning

confidence: 99%

“…Solid-state NMR allows for the investigation of materials that do not readily dissolve in traditional liquid-state NMR solvents [28]. As shown in Table 6 and Figure 7, there are some specific peaks and their approximate chemical shifts in the 13 C NMR spectra of chitin and chitosan [59,64,69,[107][108][109] N-Acetylglucosamine units usually appear in the range of 20-40 ppm. In both chitin and chitosan, carbons associated with the amide linkages can be found in the range of 150-175 ppm.…”

Section: Nuclear Magnetic Resonance Spectroscopymentioning

confidence: 99%

Update on Chitin and Chitosan from Insects: Sources, Production, Characterization, and Biomedical Applications

Mei,

Kuzhir,

Godeau

2024

Biomimetics

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Insects, renowned for their abundant and renewable biomass, stand at the forefront of biomimicry-inspired research and offer promising alternatives for chitin and chitosan production considering mounting environmental concerns and the inherent limitations of conventional sources. This comprehensive review provides a meticulous exploration of the current state of insect-derived chitin and chitosan, focusing on their sources, production methods, characterization, physical and chemical properties, and emerging biomedical applications. Abundant insect sources of chitin and chitosan, from the Lepidoptera, Coleoptera, Orthoptera, Hymenoptera, Diptera, Hemiptera, Dictyoptera, Odonata, and Ephemeroptera orders, were comprehensively summarized. A variety of characterization techniques, including spectroscopy, chromatography, and microscopy, were used to reveal their physical and chemical properties like molecular weight, degree of deacetylation, and crystallinity, laying a solid foundation for their wide application, especially for the biomimetic design process. The examination of insect-derived chitin and chitosan extends into a wide realm of biomedical applications, highlighting their unique advantages in wound healing, tissue engineering, drug delivery, and antimicrobial therapies. Their intrinsic biocompatibility and antimicrobial properties position them as promising candidates for innovative solutions in diverse medical interventions.

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Preparation and characterization of chitin and chitosan from different parts of desert locust (Schistocerca gregaria)

Elkadaoui,

Desbrieres,

Hachimi

et al. 2024

Polym. Bull.

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Physicochemical characterization of chitin extracted by different treatment sequences from an edible insect

Cited by 7 publications

References 41 publications

Punica granatum Bioactive Compounds-Loaded Chitosan Nanoparticles Exhibit Potent Antihyperglycemic Effect in Alloxan-Induced Diabetic Mice

Punica granatum Bioactive Compounds-Loaded Chitosan Nanoparticles Exhibit Potent Antihyperglycemic Effect in Alloxan-Induced Diabetic Mice

Update on Chitin and Chitosan from Insects: Sources, Production, Characterization, and Biomedical Applications

Preparation and characterization of chitin and chitosan from different parts of desert locust (Schistocerca gregaria)

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