The article presents the results of field studies and analysis of the parameters of the input and expenditure components of the water-salt balance, which makes it possible to assess the reclamation state of irrigated lands. Directly in the field, using the measurement determined the values of the input and expendable components of the water and salt balance, a tendency to improve or worsen the reclamation state of the irrigated lands of the Shuruzak massif and the Saykhunabad district of the Syrdarya region. The general water balance, the balance in the aeration zone and groundwater was compiled. Determination of water and salt balance in the aeration zone of soil and groundwater leads to the creation of optimal water-air and nutrient regimes for the development of crops and high yields. To determine the water and salt balance on the irrigated lands of the Saykhunabad region, a mathematical model was developed for the first time, based on which it is possible to predict changes in the water, salt regimes and the regime of groundwater in the irrigated massif. Their regulation is very important for determining practical measures to manage this regime in order to save irrigation water and improve the reclamation state of irrigated lands.