Physico-chemical behavior and microstructural manipulation of nanocomposites containing hydroxyapatite, alumina, and graphene oxide

Almotiri, Reim A.; Alkhamisi, Manal M.

doi:10.1007/s00339-022-05479-z

Cited by 6 publications

(3 citation statements)

References 61 publications

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“…Therefore, various materials such as alumina [14], titania [15], and silica [16] nanoparticles have been incorporated in order to increase the mechanical efficiency of HAp in hard tissue engineering. The effect of these nanoparticles in the formation of HAp-derived composites shows promising biomechanical properties for orthopedic applications [17].…”

Section: Composites Of Hydroxyapatitementioning

confidence: 99%

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

et al. 2022

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A potential material for dental restorations and bone replacements is calcium phosphate (CaP)-based ceramic material. Nevertheless, its limited ability to withstand thermal processing and weak mechanical strength prevents it from being used in hard tissue engineering. Hydroxyapatite has been extensively used as a CaP-based biomaterial in prosthetic applications. On the other hand, zirconia is an inorganic material that combines outstanding mechanical capabilities with bioinert characteristics. In the present investigation, we demonstrated the reinforcement of zirconia in biomimetic hydroxyapatite (HAp) using a specially designed stir-type hydrothermal reactor to improve the biocompatibility and mechanical stability of bare hydroxyapatite. X-ray diffraction (XRD) analysis showed distinct peak shifts around 31° and 60°, which confirmed the formation of a nanocrystalline HAp-Zirconia composite without any intermediate phases. The size of the synthesized nanocomposite was found to be 30 nm using TEM. Further, the d-spacing value calculated from high-resolution transmission electron microscope (HRTEM) images corresponded to the distinct planes of the HAp (211) and zirconia (311) phases, respectively, in the composite powder. The in vitro cytotoxicity study revealed excellent biocompatibility with MG-63 human osteoblasts. Hence, the zirconia reinforced hydroxyapatite (HZ1) prepared in the present work could be utilized as a successful approach in a variety of hard tissue engineering applications.

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Section: Composites Of Hydroxyapatitementioning

confidence: 99%

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

et al. 2022

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“…HAp has the general formula (Ca 10 (PO 4 ) 6 (OH) 2 ). It is conceivable for HAp to have either a monoclinic or hexagonal structure [2] . Human and animal bones contain hexagonal HAp.…”

Section: Introductionmentioning

confidence: 99%

“…It is conceivable for HAp to have either a monoclinic or hexagonal structure. [2] Human and animal bones contain hexagonal HAp. Prepared hydroxyapatite is recognized as one of the most constructive resources for the fabrication of osteointegrated implants because of its chemical resemblance.…”

Section: Introductionmentioning

confidence: 99%

Excellent Photocatalytic Activity of a Novel Hydroxyapatite Based Composite (ZnFe₂O₄/HAp‐Sn²⁺) Towards Degradation of Ofloxacin and Norfloxacin Antibiotics

et al. 2022

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Antibiotic contamination in wastewater has become a matter of great concern due to the rapid industrial progress. The majority of antibiotic pollution in the environment occurs due to the waste from animal farms, aquaculture, sewage from antibiotic factories and hospitals. Therefore, it is vital to develop efficient and ecologically friendly photocatalysts for the degradation of such pollutants. In this paper, we report synthesis of ZnFe 2 O 4 /HAp-Sn 2 + , a novel nanocomposite by three-step processes using hydrothermal treatment followed by calcination. The as-synthesized composite was characterized by Fourier transform infrared spectroscopy (FT-IR), ultraviolet diffused reflectance spectroscopy (UV-DRS), polycrystalline (or power) X-ray diffraction (PXRD), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), thermogravimetric analysis (TGA) and X-ray photoelectron spectroscopy (XPS). The as-prepared composite exhibited excellent photocatalytic activity in the degradation of two antibiotics namely ofloxacin (OFL) and norfloxacin (NFL) under natural sunlight without use of any oxidizing or reducing agents. Scavenger studies were also carried out to ascertain the active radicals such as superoxide and hydroxyl radical during the photodegradation process.

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Nanocomposites in Combating Antimicrobial Resistance

Varghese,

Mathew,

Balachandran

2024

Nanotechnology Based Strategies for Combating Antimicrobial Resistance

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Physico-chemical behavior and microstructural manipulation of nanocomposites containing hydroxyapatite, alumina, and graphene oxide

Cited by 6 publications

References 61 publications

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

Excellent Photocatalytic Activity of a Novel Hydroxyapatite Based Composite (ZnFe₂O₄/HAp‐Sn²⁺) Towards Degradation of Ofloxacin and Norfloxacin Antibiotics

Nanocomposites in Combating Antimicrobial Resistance

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Physico-chemical behavior and microstructural manipulation of nanocomposites containing hydroxyapatite, alumina, and graphene oxide

Cited by 6 publications

References 61 publications

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

Synthesis of Hydroxyapatite (HAp)-Zirconia Nanocomposite Powder and Evaluation of Its Biocompatibility: An In Vitro Study

Excellent Photocatalytic Activity of a Novel Hydroxyapatite Based Composite (ZnFe2O4/HAp‐Sn2+) Towards Degradation of Ofloxacin and Norfloxacin Antibiotics

Nanocomposites in Combating Antimicrobial Resistance

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Excellent Photocatalytic Activity of a Novel Hydroxyapatite Based Composite (ZnFe₂O₄/HAp‐Sn²⁺) Towards Degradation of Ofloxacin and Norfloxacin Antibiotics