Physico-Chemical and Electrochemical Characterizations of a Trachyte in the Far North Region of Cameroon for Possible Electroanalytical and Environmental Purposes

Dai-Yang, Lemankréo; Pengou, Martin; Tcheumi, Hervé L.; Nguihdama, D; Wahabou, Abdoul; Ngatchou, Beaufils Ngana; Wamba-Tchio, Odilon Romaric; Kouamo, H. Tchakoute; Nanseu‐Njiki, Charles Péguy; Ngameni, Emmanuel

doi:10.1007/s10904-020-01706-3

Cited by 1 publication

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“…In presence of [Fe(CN) 6 ] 3-, the current density peak (1.250×10 -7 A.cm -2 ) materialize the oxidation of [Fe(CN) 6 ] 4ions [20]. The current density peak around -2.345×10 -7 A.cm -2 are attributable to the reduction of [Fe(CN) 6 ] 3ions to [Fe(CN) 6 ] 4- [21].…”

Section: Electro Activity Of the Carbon-clay Paste Electrode Doped Wi...mentioning

confidence: 95%

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Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)

Justin¹,

Valery²,

Ramses³

et al. 2022

AJCBE

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The aim of this work is to prepare and characterize a carbon-clay paste electrode doped with Titanium Oxide (CPEA/TiO 2 ). This electrode is used to study the electrochemical behavior of drugs such as Chloroquin, Azithromycin and Hydroxychloroquin. The morphological, structural and functional characteristics of this electrode were carried out using X-ray diffraction (XRD), selected area electron diffraction (SAED), scanning electron microscopy (SEM), Fourrier transform infrared spectroscopy (FTIR). The electrochemical characterization was made by Cyclic Voltammetry (CV) in the potential range [-0.1V; 0.9V], in a phosphate buffer solution (0.1M; pH = 6.4); focused on the detection of an inorganic complex (ion [Fe(CN) 6 ] 3-(1mM)). The application was made focused on the detection of organic macromolecules such as azithromycin (AZI), chloroquin (CHL) and hydroxychloroquin (HYC). CPEA/TiO 2 was then subjected to electroanalysis in the same concentrations of the combinations AZI+CHL and AZI+HYC. However, in the presence of analyte the phenomena are irreversible with a dominance of oxidation phenomena. The electroactivity of the drugs used initially concerns the hydroxyl groups, observed around 0.050V (oxidation potential of the hydroxyl function in an intermediate form) and 0.560V (oxidation potential of the intermediate and in the carbonyl group). Secondly, the electro activity of the tertiary amine is highlighted by the potential value of 0.690V (attributable to the oxidation of the tertiary amine into an ammonium hydroxyl derivative). Current densities are more pronounced, which suggests a new molecule with significant electro activity. The oxidation mechanism is proposed. The electroactivity of the excipients (Lactose and Starch) used in these drugs is not negligible and evolves when going from one drug to two. However, the excipients are less noticeable in the AZI+HYC combination than in AZI+CHL.

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Section: Electro Activity Of the Carbon-clay Paste Electrode Doped Wi...mentioning

confidence: 95%

“…At the interval of the chosen potential, no oxido-reduction phenomenon is perceptible on the surface of the modified electrode. The different voltammograms are stable and reproducible [21,22] showing the electroactive nature of CPEA/TiO 2 .…”

Section: Electro Activity Of the Carbon-clay Paste Electrodementioning

confidence: 99%

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)

Justin¹,

Valery²,

Ramses³

et al. 2022

AJCBE

View full text Add to dashboard Cite

show abstract

Physico-Chemical and Electrochemical Characterizations of a Trachyte in the Far North Region of Cameroon for Possible Electroanalytical and Environmental Purposes

Cited by 1 publication

References 10 publications

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)

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Physico-Chemical and Electrochemical Characterizations of a Trachyte in the Far North Region of Cameroon for Possible Electroanalytical and Environmental Purposes

Cited by 1 publication

References 10 publications

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO&lt;sub&gt;2&lt;/sub&gt;)

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO&lt;sub&gt;2&lt;/sub&gt;)

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Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)

Electrochemical Behavior of Chloroquin, Azithromycin and Hydroxychloroquin onto Carbon-Clay Paste Electrode Doped with Titanium Oxide (TiO<sub>2</sub>)