Physical training alters the reactions of haemostasis system to hypoxia

Abstract

Physical pretraining of 102 Wistar rats during 30 days altered the reactions of haemostasis system to one-day hypobaric hypoxia. Decreased level of thrombinemia, ameliorated platelete, and plasma hаemostasis, increased anticoagulation, and fibrinolytic activity were observed. These changes were more pronounced in the experimental group of animals having experienced intensive physical training.

Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions

“…It has been found that after 10–15 min of a single training session on a stationary bicycle, fibrinopeptide A level does not increase despite the activation of coagulation and fibrinolysis. Platelet aggregation ability can also increase during an appreciably strenuous single training session [ 79 , 80 ]. Nonspecific changes, including those in the blood aggregate state regulation system, arise from exposure to any high-intensity factor and are accompanied by rearrangement of the defense system.…”