Abstract:This study was conducted to improve the dissolution of ketoprofen in nanosuspensions. Ketoprofen nanosuspensions were prepared by a solvent evaporation method using polyvinylpyrrolidone (PVP) and Tween 80 as stabilizers at varied ratios with ketoprofen. Ethanol was used as a solvent for ketoprofen. Physical stability and dissolution of the produced ketoprofen nanosuspensions and conventional suspension were analyzed and compared. The parameters evaluated for their stability for a three-month period were pH, ap… Show more
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